PLLA/PMMA blend in polymer nanoparticles: influence of processing methods

Peres, Luana Becker; Peres, Laize Becker; Faria, Tatiany J. de; Assis, João Vitor de; Almeida, Mauro Vieira de; Gonçalves, Odinei Hess; Araújo, Pedro Henrique Hermes de; Sayer, Cláudia

doi:10.1007/s00396-017-4140-7

Cited by 7 publications

(3 citation statements)

References 51 publications

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“…Combining more than one material can provide the nanoparticles with unique properties. Additionally, the variety of blend compositions and formulations make nanoparticles with variable drug delivery capabilities to incorporate hydrophobic and hydrophilic molecules with different molecular weights to control their release [ 44 , 45 ].…”

Section: Nanoparticles’ Preparation and Drug Loadingmentioning

confidence: 99%

Hybrid Systems of Nanofibers and Polymeric Nanoparticles for Biological Application and Delivery Systems

et al. 2023

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Nanomedicine is a new discipline resulting from the combination of nanotechnology and biomedicine. Nanomedicine has contributed to the development of new and improved treatments, diagnoses, and therapies. In this field, nanoparticles have notable importance due to their unique properties and characteristics, which are useful in different applications, including tissue engineering, biomarkers, and drug delivery systems. Electrospinning is a versatile technique used to produce fibrous mats. The high surface area of the electrospun mats makes them suitable for applications in fields using nanoparticles. Electrospun mats are used for tissue engineering, wound dressing, water-treatment filters, biosensors, nanocomposites, medical implants, protective clothing materials, cosmetics, and drug delivery systems. The combination of nanoparticles with nanofibers creates hybrid systems that acquire properties that differ from their components’ characteristics. By utilizing nanoparticles and nanofibers composed of dissimilar polymers, the two synergize to improve the overall performance of electrospinning mats and nanoparticles. This review summarizes the hybrid systems of polymeric nanoparticles and polymeric nanofibers, critically analyzing how the combination improves the properties of the materials and contributes to the reduction of some disadvantages found in nanometric devices and systems.

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Section: Nanoparticles’ Preparation and Drug Loadingmentioning

confidence: 99%

Hybrid Systems of Nanofibers and Polymeric Nanoparticles for Biological Application and Delivery Systems

et al. 2023

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“…According to the authors, these particles showed efficiency above 85 % for carrying a hydrophobic drug. [12] The production of core-shell polymer particles for biotechnological applications, especially those involving enzymatic immobilization, must consider biocompatibility, [13] equilibrium morphology, synthesis method, particle size, and surface functionalization of the shell polymer. [14,15] Therefore, the main synthesis techniques used to produce core-shell polymer particles and their characteristics will be discussed below.…”

Section: Core-shell Polymeric Particlesmentioning

confidence: 99%

“…Using only the miniemulsion technique, the authors could produce immiscible and amorphous particles with a core‐shell morphology, where a PLLA shell covered the PMMA core. According to the authors, these particles showed efficiency above 85 % for carrying a hydrophobic drug [12] …”

Section: Core‐shell Polymeric Particlesmentioning

confidence: 99%

A Comprehensive Review on Core‐Shell Polymeric Particles for Enzyme Immobilization

et al. 2022

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The search for ideal solid support that promotes enzyme stability, easy separation and reuse cycles in different processes has grown widely. In this sense, core‐shell polymer particles draw attention because they are already widely used in adsorption, catalysis, and drug delivery, due to their remarkable advantages in surface properties adjustment, excellent mechanical stability, and high chemical resistance, as a result of the combination of the characteristics of the polymers that form the core and shell of the structure. Thus, this review article provides an overview of the synthesis processes of these particles, highlighting the characteristics that can be obtained from each synthesis technique, as well as the most recently used techniques to obtain polymeric particles with core‐shell morphology. The advantages and main challenges for the application of these structures in the immobilization of enzymes are also discussed, providing a general summary of what has been explored in the literature. Despite the potential of application, the use of these materials in the immobilization of enzymes is still little explored, with studies focused mainly on lipases and around the same classes of polymers. Therefore, there is an opportunity window regarding the investigation of the immobilization of other enzymes of commercial interest on these polymeric supports.

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Biopolymeric Material‐based Blends: Preparation, Characterization, and Applications

Rehman¹,

Rehman

2019

Bio Monomers for Green Polymeric Composite Materials

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PLLA/PMMA blend in polymer nanoparticles: influence of processing methods

Cited by 7 publications

References 51 publications

Hybrid Systems of Nanofibers and Polymeric Nanoparticles for Biological Application and Delivery Systems

Hybrid Systems of Nanofibers and Polymeric Nanoparticles for Biological Application and Delivery Systems

A Comprehensive Review on Core‐Shell Polymeric Particles for Enzyme Immobilization

Biopolymeric Material‐based Blends: Preparation, Characterization, and Applications

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