“…Calcium orthophosphate bioceramics play important roles in the replacement and regeneration of bone tissue due to their chemical composition and similarity to mammalian bones and teeth. The main applications of these bioceramics include healing of bone defects, fracture treatment, total joint replacement, bone augmentation, orthopaedics, craniomaxillofacial reconstruction, spinal surgery, otolaryngology, ophthalmology, and percutaneous devices [1][2][3]. Calcium orthophosphates (CaPO 4 ), such as tricalcium phosphate (TCP), hydroxyapatite, dicalcium phosphate dihydrate, and octacalcium phosphate (OCP), have been used in various shapes, such as coatings, films, layers, and scaffolds, to improve implant biocompatibility and osteoconductivity [4,5].…”