1982
DOI: 10.1016/s0022-5347(17)52990-0
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Pneumocystis Carinii Pneumonia and Mucosal Candidiasis in Previously Healthy Homosexual Men. Evidence of a New Acquired Cellular Immunodeficiency

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Cited by 349 publications
(404 citation statements)
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“…Both herpesvirus II and papillomavirus (causing condylomata acuminata) are possible candidates by virtue of their association with cervical cancer (Graham et al, 1982;Reid et al, 1982;Hulka, 1982). Condylomata have been described in case reports as apparent precursors to squamous carcinomas of the anus (Shelly & Wood, 1981;Prasad & Abcarian, 1980;Siegel, 1962;Oriel & Whimster, 1971 Since the excess risk for anal cancer in single males exists for older as well as younger men and has been observed over at least the last 10 years, and since squamous tumours such as anal carcinoma probably require several years to develop, it seems unlikely that anal cancer is related to AIDS (CDC, 1982;Gottlieb et al, 1981). Nonetheless, we cannot completely rule out this possibility.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Both herpesvirus II and papillomavirus (causing condylomata acuminata) are possible candidates by virtue of their association with cervical cancer (Graham et al, 1982;Reid et al, 1982;Hulka, 1982). Condylomata have been described in case reports as apparent precursors to squamous carcinomas of the anus (Shelly & Wood, 1981;Prasad & Abcarian, 1980;Siegel, 1962;Oriel & Whimster, 1971 Since the excess risk for anal cancer in single males exists for older as well as younger men and has been observed over at least the last 10 years, and since squamous tumours such as anal carcinoma probably require several years to develop, it seems unlikely that anal cancer is related to AIDS (CDC, 1982;Gottlieb et al, 1981). Nonetheless, we cannot completely rule out this possibility.…”
Section: Discussionmentioning
confidence: 99%
“…There was no consistent excess risk for single women as there was for single men (Table IV) (CDC, 1982;Gottlieb et al, 1981 (7 versus 4.8) tumours, and it occurred primarily among males who were single (8 versus 3.8) or whose marital status was not recorded on their hospital charts (4 versus 0.3). All cases were symptomatic and none appeared to have been diagnosed as a result of screening.…”
Section: Methodsmentioning
confidence: 98%
“…Since the first report of HIV infection in 1981 [5], several classifications have been proposed for a staging system of HIV-infected patients [6][7][8]. In the present patient, candidiasis of the esophagus was observed in an endoscopic examination.…”
Section: Discussionmentioning
confidence: 71%
“…The level of these cells in the peripheral blood is therefore the single most important parameter for monitoring disease associated with HIV infection. Ever since the first case report on acquired immunodeficiency syndrome (AIDS) (46), flow cytometry has remained the gold standard for CD4 T-cell enumeration in HIV disease. Recently, however, this virtually unassailable position has been placed into jeopardy.…”
Section: Quantitative Flow Cytometry the Methods Of Choice For Affordmentioning
confidence: 99%