A 69-year-old male with a history of chronic obstructive pulmonary disease, esophageal cancer status post-resection with gastric conduit, subsequent anastomotic leak with fistula treated with esophageal stenting who presented to our tertiary care hospital as transfer with computed tomography (CT) (figure 1) evidence of multifocal pneumonia, pneumomediastinum, and pneumopericardium after receiving ceftriaxone and metronidazole. His vital signs on arrival included: temperature = 36.8 • C, blood pressure = 104/75 mm Hg, heart F I G U R E 1 Pneumomediastinum and hydropneumopericardium in association with esophageal stent in the gastric pull-through This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.