Poisoning in children 3: Common medicines

Riordan, Michael; Rylance, G; Berry, Katherine

doi:10.1136/adc.87.5.400

Cited by 23 publications

(18 citation statements)

References 19 publications

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“…Ülkemizde ve Dünya'da yapılan çalışmalar incelendiğinde çocukluk yaş grubunda zehirlenmenin en sık nedeninin ilaçlar olduğu görülmektedir [2,3,24]. Amerika zehir kontrol merkezi raporlarına göre 1998 yılında 18 yaş altında görülen 1,5 milyondan fazla zehirlenmenin ilaçlara bağlı olduğu ve 56 ölüm vakasının %66'sının ilaçlara nedeniyle olduğu rapor edilmiştir [25].…”

Section: Discussionunclassified

“…Bizim çalışmamızda ise salisilat sı-ralamada oldukça geride (3 vaka, %4) kaldığı tespit edildi. Bunun nedeni çocukluk yaş grubunda geçmiş yıllarda ateş düşürücü olarak kullanılan aspirinin Reye sendromu riski nedeniyle kısıtlı kullanılması sonucunda salisilat zehirlenmelerinin azalmasıdır [24] . Salisilatın yerine artık parasetamol kullanıl-makta ve çalışmamızda da parasetamole bağlı zehirlenme ilaçlar içinde 3. sırada (8 vaka, %11,7) yer almaktadır.…”

Section: Discussionunclassified

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Isparta bölgesindeki çocukluk çağı zehirlenmelerinin değerlendirilmesi

Dereci¹,

Koca²,

Gençer³

et al. 2015

Dicle Med J

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Objective: The purpose of this study was to assess the patients who presented with intoxication case to our Children Emergency Department of Süleyman Demirel University Medical Faculty Hospital, retrospectively. Methods:The patients, who were admitted to our children emergency service between the dates July 2013 and July 2014 were searched retrospectively. The age, sex, the admission time, the admission duration, the way of intoxication, symptoms, the items caused intoxication, the aim of taking the item and the hospital stay of the cases were evaluated.Results: For the study, the files of 82 patients aged from 1 to 18 years (mean 8,9±6,3 years) were scanned; 50 (60.9%) cases were female, 32 (39.1%) were male. Intoxication cases constituted 3.6% of all cases admitted to the children's emergency unit over one year period. A high proportion (51%) of intoxication cases were between 1 and 5 years of age. Thirty of the thirty (100%) patients that were intoxicated because of a suicide attempt were girls and all of them were over 12 years of age. The most common substance for intoxication was drugs (76%), followed by insecticides and herbal (6.5%). Amon the medication, cold relief drugs (14%), antidepressant (13%) and paracetamol (12%) drugs were most common. Conclusion:Poisoning shows a peak in two periods of childhood and adolescence in this study. We think that accidental ingestion in childhood can be prevented by parents' education and simple precautions in general. In addition, we recommend that families should demonstrate appropriate approaches, especially with regards to the psychology of adolescent girls, and, if necessary, get help from a specialist. Sonuç: Bu çalışmada çocukluk çağı zehirlenmelerinin oyun çağı ve adölosan dönem olmak üzere iki dönemde pik yaptığı tespit edilmiştir. Ailelerin eğitimi ve alınacak basit önlemlerle oyun cağındaki çocukların kaza sonucu olan zehirlenmelerinin büyük ölçüde önlenebileceğini düşünmekteyiz. Ayrıca, ailelerin adölesan yaş grubunda ki kız çocuklarının psikolojilerine uygun davranması ve gerekli durumlarda konusunda uzman olan kişilerden yardım almaları gerekmektedir.Anahtar kelimeler: Çocukluk çağı, Isparta bölgesi, zehirlenme

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Section: Discussionunclassified

Isparta bölgesindeki çocukluk çağı zehirlenmelerinin değerlendirilmesi

Dereci¹,

Koca²,

Gençer³

et al. 2015

Dicle Med J

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“…[1][2][3][4][5][6][7][8][9][10] In developing countries, poisoning has also been recognised as a major health problem among children and adolescents. [11][12][13] Ahmed and Andersson compared the mortality rates of unintentional injuries, including poisoning, in countries with different income levels, and found that poisoning is the second most common cause of death in all lower and upper middle income countries among the [15][16][17][18][19][20][21][22][23][24] year age group. 12 Certain poison types of medicinal and non-medicinal substances have been identified as common agents in poisoning in children and adolescents.…”

mentioning

confidence: 99%

“…12 Certain poison types of medicinal and non-medicinal substances have been identified as common agents in poisoning in children and adolescents. [14][15][16][17] Riordan et al reviewed the literature on childhood poisoning and identified several groups of medicinal substances as the most common. 14 15 These included analgesics, anti-inflammatory agents, psychotropic drugs such as antidepressants, and benzodiazepines related agents.…”

mentioning

confidence: 99%

Childhood and adolescence poisoning in NSW, Australia: an analysis of age, sex, geographic, and poison types

Lam

2003

Inj Prev

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Objective: This study aims to investigate whether there is any association between the types of poison substances and geographic locations for different age groups and sex. Design: This is a population based epidemiological study utilising routinely collected inpatient statistics. Setting: Data are collected as part of the routine vital health information system via all hospitals in New South Wales (NSW), Australia. Patients: All patients aged between 0-19 years who were admitted to a hospital because of poisoning by the four major types of substances that were defined in the study in NSW in 2000. Main results: The standardised incidence ratios of poisoning related hospitalisation between metropolitan and rural areas varied across different poison types when compared with the NSW average. While there are few differences between metropolitan and rural areas for analgesic and chemical related poisoning admissions across different age groups and sex, differences in the standardised incidence ratios between geographic locations for psychotropic and venom related poisoning admissions were found. No significant difference in standardised mortality ratios were found between metropolitan and rural areas except for females in the 10-14 years age group (standardised mortality ratio 3.24, 95% confidence interval 1.69 to 6.21). Conclusions:The results obtained in this study, on the whole, provide some evidence for an association between poison types and geographic locations for psychotropic and venom related poisoning. P oisoning has been identified as one of the major causes of childhood and adolescence hospital emergency presentations and admissions in most developed countries including the United States, United Kingdom, and Australia.

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“…[1][2][3][4][5][6][7][8][9][10] According to the 2003 American Association of Poison Control Centers Toxic Exposures Surveillance System data, which provide a wide coverage of the U.S. territory, there are approximately 2.4 million exposures, and 93 and 52% of them occurs in the household and in children younger than six years, respectively. 1 Most exposures in this age group are unintentional (99.4%), with less morbidity and mortality if compared to other pediatric age groups; however, among adolescents, 45.9% of the exposures were intentional.…”

Section: Introductionmentioning

confidence: 99%

Exposições tóxicas agudas em crianças: um panorama

Bucaretchi¹,

Baracat²

2005

J. Pediatr. (Rio J.)

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Summary of the findings: Acute toxic exposure in children is a common event, mainly in children under six years of age. Death is rare. Although widely employed, there is no evidence that gastrointestinal decontamination and multiple-dose activated charcoal improve the outcome of poisoned patients. Very few efficient antidotes are used on a consistent basis, and some of them are very expensive and not available in Brazil.Conclusions: Ipecac syrup and cathartics should not be administered on a routine basis in acute toxic exposures in outpatient treatment. Excluding the contraindications, single-dose activated charcoal and gastric lavage may be considered within one hour of ingestion if a patient ingested a potentially toxic amount or a potentially lethal amount, respectively. Whole bowel irrigation, multiple-dose activated charcoal and urine alkalinization may be considered in a few situations. Fomepizole and octreotide are safe and efficient antidotes, which can be used in the treatment of alcohol (methanol and ethylene glycol) and sulfonylureas poisoning, respectively. J Pediatr (Rio J). 2005;81(5 Suppl):S212-S222: Poisoning, gastrointestinal decontamination, charcoal, antidotes, children.

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Poisoning in children 3: Common medicines

Cited by 23 publications

References 19 publications

Isparta bölgesindeki çocukluk çağı zehirlenmelerinin değerlendirilmesi

Isparta bölgesindeki çocukluk çağı zehirlenmelerinin değerlendirilmesi

Childhood and adolescence poisoning in NSW, Australia: an analysis of age, sex, geographic, and poison types

Exposições tóxicas agudas em crianças: um panorama

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