Polarimetric characterization of ultra-high molecular weight polyethylene (UHMWPE) for bone substitute biomaterials

Firdous, S.; Fuzail, Muhammad; Nawaz, M.

doi:10.1016/j.ijleo.2009.10.008

Cited by 21 publications

(11 citation statements)

References 14 publications

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“…The PSG-emerging light focused to the sample and the sample and scattered light collected by the PSA unit for the analysis of the polarization state of light and relayed for spectrally resolved signal detection. The PSA unit comprises of the same polarization components with a fixed linear polarizer (P2) and a computer controlled rotating quarter wave plate (QWP2) as shown in Figure 1 [34].…”

Section: Methodsmentioning

confidence: 99%

Optical Polarimatic Characterization of Zinc Oxide Nanorods as a Photosensitizer for Photodynamic Therapy

Firdous

2018

CTOIJ

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The role of nanoparticles in diagnostic and treatment of cancer and other malignant diseases is gaining much research attention. The zinc oxide nanorods (ZnO NRs) are one of the most studied and promising semiconductor materials for applications in materials and medical sciences. In this study, we present optical properties of ZnO nanorods using Mueller matrix polarimetry to be suitable for its application in photodynamic therapy (PDT). Mueller matrix spectroscopic system capable of acquiring complete polarization information from single nanoparticle to nanostructure in term of transmittance, depolarization, retardance, and polarizance.The polarization properties measured from 400 to 800nm wavelength of light described decreasing trend of transmission at a wavelength range of 400nm to 530nm. This behavior of light describes Rayleigh scattering in the region and shows ZnO nanorods of relatively smaller diameter to excitation wavelength. Depolarization index decreases from 0.98 to 0.84 on 400nm to 650nm showing bulk scattering of light from randomly distributed ZnO nanorods. Slight change in retardance from 445nm to 550nm shows that light having low frequency and high wavelength passes readily than the high frequency light presenting that ZnO nanorods are strong, compact and composite material. Diattenuation magnitude increases with the increase in wavelength from 400nm to 750nm and changes abruptly at a wavelength range from 750nm to 800nm. This irregular trend indicates that ZnO nanorods are birefringent and anisotropic. These measured polarized properties proved that ZnO NRs are suitable to use as photosensitizer in PDT for diagnostic and treatment of cancer and other malignant diseases.

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Section: Methodsmentioning

confidence: 99%

Optical Polarimatic Characterization of Zinc Oxide Nanorods as a Photosensitizer for Photodynamic Therapy

Firdous

2018

CTOIJ

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“…To perform accurate polarimetry, all the issues necessary for careful and accurate radiometry must be considered together with many additional polarization issues. Mueller matrix polarimetry yields four optical parameters, namely depolarization coefficient, linear retardance, optical activity, and diattenuation, which can be used to characterize the tissues or turbid media [22][23][24][25][26][27][28][29][30][31][32][33][34]. We represented very interesting results from the dengueinfected whole blood by exploiting the depolarization nature of polarized light in whole blood; this can be used for the discrimination between the healthy and viral infection diseased blood samples [5].…”

Section: Mueller Matrix Polarimetrymentioning

confidence: 99%

Optical Diagnostic of Dengue Virus Infected Human Blood using Raman, Polarimetric and Fluorescence Spectroscopy

Firdous¹,

Anwar²

2017

Dengue - Immunopathology and Control Strategies

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In this chapter, we present the optical diagnosis of normal and dengue viral-infected human blood using Raman, Polarimetric, Transmission, and Fluorescence Spectroscopic techniques. The possibility of using light in diagnosis and treating illness has been known for thousands of years. The properties of light and lasers provided many modern applications at home, in industry, and in the field of medicine. Laser use in the field of medicine is large and steadily growing. This growth is based on the versatility of laser light. Efficient and accurate diagnosis of dengue is of primary importance for clinical care. A range of laboratory diagnostic methods has been developed to support patient management and disease control. The choice of diagnostic method depends on the purpose for which the testing is done, the type of laboratory facilities and technical expertise available, costs, and the time of sample collection. The dengue viral infection is mostly diagnosed through laboratory tests; these tests include detection of the virus, virus antigen, anti-dengue virus antibody, complement fixation test, neutralization tests, and detection of virus nucleic acid. As dengue infection most rapidly increases in different regions, early diagnostic confirmation of dengue infection in patients allows for timely clinical intervention, etiological investigation, and disease control. Hence, diagnosis of dengue disease during the acute phase should be a priority and is a public health concern. Lasers and optics have many applications in medical sciences; diagnosis and treatment of diseases with lasers and light are latest and noninvasive techniques. Development of light-based apparatus has evolved into tools for improved diagnosis and treatment modalities in medical sciences. The methods of the laser spectroscopy make it possible to obtain direct information regarding the structure and dynamics of the functional groups of biomolecules. Development of new light sources, optics, and diode laser of different wavelengths makes them attractive for spectroscopy of biological molecules. In our study, more than 600 dengue viral-infected blood or blood sera samples and 25 non-dengue healthy blood samples were analyzed using four different optical methodologies. In the first study, Raman spectrum peaks for normal samples observed at 1527, 1170, and 1021 cm −1 show the presence of different biological materials, including lipids, carbohydrates, skeletal CC stretch of acyl chains, and

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“…Ultra-high molecular weight polyethylene (UHMWPE) is one of the promising matrix materials due to its high chemical inertness, the highest wear resistance of any thermoplastics, low friction coefficient and bioinertness make it the material of choice for hip joints and knee joints. Other excellent properties, such as low density, high strength, high modulus, good abrasion, and chemicals resistance [3,4]. To further improve its mechanical properties and tribological response, fillers/reinforcements are incorporated into the polymer [5].…”

Section: Introductionmentioning

confidence: 99%

An Investigation on UHMWPE-HAp Composites Manufactured by Solution-Gelation Method

Efe¹,

Ibrahim²,

Türk

et al. 2020

Sakarya University Journal of Science

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In this study, HAp reinforcement into UHMWPE matrix having 1.0 % wt. mass and its effects on microstructural and mechanical properties of the UHMWPE composites were investigated. UHMWPE composites reinforced with 0.5, 1 and 2.0 wt. % nano HAp powders, respectively were successfully produced by solution and gelation method. SEM studies showed that HAP nano particles were homogenously distributed into UHMWPE matrix and good cross-linked with the matrix. SEM-map EDS analysis confirmed SEM. FTIR results revealed that HAp incorporation into matrix was conducted and crystallization of UHMWPE increased by increment in amount of HAp results in deepening crystallization peaks at nearby 500 and 1500 cm -1 . DSC results, which is useful technique to determine the variation of melting point and crystallization ratio of UHMWPE composites, indicated that there was no remarkable change in melting points of composites, while crystallinity of the samples generally showed slight increase by increasing amount of nano HAp particles. The tensile test instrument was utilized to determine elastic modulus of the samples and their elastic modulus were raised from 1050 to 1900 MPa with higher HAp reinforcement. It can be concluded that UHMWPE-1 % wt. HAp composites have promising results by being paired with crystallinity and elastic modulus.

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Polarimetric characterization of ultra-high molecular weight polyethylene (UHMWPE) for bone substitute biomaterials

Cited by 21 publications

References 14 publications

Optical Polarimatic Characterization of Zinc Oxide Nanorods as a Photosensitizer for Photodynamic Therapy

Optical Polarimatic Characterization of Zinc Oxide Nanorods as a Photosensitizer for Photodynamic Therapy

Optical Diagnostic of Dengue Virus Infected Human Blood using Raman, Polarimetric and Fluorescence Spectroscopy

An Investigation on UHMWPE-HAp Composites Manufactured by Solution-Gelation Method

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