Polskie rekomendacje diagnostyki i leczenia zróżnicowanego raka tarczycy u dzieci

Abstract

These recommendations, concerning the diagnostics and treatment of differentiated thyroid cancer (DTC) in children and adolescents, are the first such Polish guidelines created by the group of delegates of National Societies that declare their willingness to participate in their preparation. The signal that gathered specialists involved in the medical care of children with thyroid carcinoma was the publication of the guidelines of the

Papillary thyroid cancer in three children

“…Differentiated thyroid cancer (DTC) is a major TC in children [3]. New incidences of DTC in people under 19 years of age comprise 2.3% of all thyroid cancers (National Cancer Registry data from 2003-2013) [4]. In recent years there has been an increase in TC rates both in Poland and in the rest of the world.…”

“…Epidemiologic studies indicate that the incidence of DTC in children and adults is increasing by 6.5% per year [5,6] and is estimated to be 0.54 cases per 100,000 people [2,7]. Unlike in adults, the majority of paediatric cases represent papillary thyroid cancer (PTC) in various histological variants, and account for around 90% of all cases of DTC in children [4]. In patients over 15 years of age, PTC is diagnosed 10-13 times more often than in children under 10 years old [8,9].…”

“…In patients over 15 years of age, PTC is diagnosed 10-13 times more often than in children under 10 years old [8,9]. Papillary thyroid cancer is the second most frequently diagnosed solid cancer in girls, and the eighth in boys [9,4]. It does not clearly correlate with gender before adolescence.…”

Survey on Paediatric Differentiated Thyroid Cancer Care in Europe

“…However, in some cases, the initial thyroid surgery is performed outside these 4 specific centres. Based on the data and the Polish experience with paediatric DTC, “Diagnostics and treatment of differentiated thyroid carcinoma in children – Guidelines of Polish National Societies” has been published [11]. Total thyroidectomy is recommended in all children diagnosed with DTC including tumour stage pT1a, tumour ≤1 cm limited to the thyroid, however only this last mentioned group does not receive adjuvant radio-iodine treatment.…”

“…To all of the other patients, age- and weight-adjusted 131 I ablation therapy has been offered after recombinant human TSH. Life-long follow-up is advocated [11]. …”