Poly Fused/Isolated/Spiro Sulphur Compounds of Quinone and Their Biological Activity

Monocyclic β-Lactams: New Structures for New Biological Activities

“…The synthesized scaffold was screened for in vitro anti-filarial activity against Brugia 40 60 1940 1945 1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 year year N O Another example of 4-spiro-azetidinone derivative is compound 14 which showed significant antibacterial potency against Grampositive strains whereas Gram-negative bacteria revealed weak susceptibility [26]. In Fig.…”

A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

“…El‐Kanzi et al [73] reported a reaction of 182 with methyl iodide in presence of KOH yielding methylated derivative 183 which on cyclocondensation with chloroacetyl chloride in presence of triethylamine gave thiazinane derivative 184 . The condensation reaction of 184 and nitroso compounds 144 in ethanol gave corresponding hydrazides 185 which was further condensed with thioglycolic acid to afford the spirothiazolidinones 186 (Scheme 42).…”

Synthesis of 1H‐Thiopyrano[4,3‐c]quinoline Scaffold via One‐pot Three‐component Cyclization

“…Among quinoline annulated derivatives, thiopyranoquinolines have attracted the attention of synthetic chemists and pharmaceutical designers owing to their unique properties. These compounds have medicinal effects and bioactivities such as antioxidant, antibacterial, anticancer, anti‐viral, cytotoxicity, anti‐Alzheimer, fungicidal, inhibitor, antimicrobial, antagonistic, and antitumor . For example, thiopyrano[2,3‐ b ]quinolines A and B have been identified as antioxidant and mGlu 1 receptor antagonist, respectively.…”