Poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide), N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide as new efficient reagents for conversion of alcohols to THP ethers and aldehydes to oxazoline compounds

Abstract

This paper is concerned with an easy preparation of THP ethers from primary, secondary and tertiary alcohols and oxazoline compounds from various aldehydes using poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide), N,N,N', as new and efficient reagents under ambient conditions without over-oxidation.

Trichloroisocyanuric acid as an efficient homogeneous catalyst for the chemoselective synthesis of 2-substituted oxazolines, imidazolines and thiazolines under solvent-free condition

“…The corresponding 2-substituted thiazolines were generated in good to excellent yields (Table I, entries [15][16][17][18][19][20][21][22][23][24]. The effects of temperature and solvent were also investigated.…”

“…Oxazolines, imidazolines and thiazolines are important substructures in a large number of biologically active natural products. [15][16][17][18][19][20][21][22][23][24][25] Although some of these procedures have been successfully used for the synthesis of these heterocycles, most of them suffer from disadvantages such as: strong acidic conditions, long reaction times, low yields of products, use of complex and expensive re-agents and toxic solvents. In addition to these serious affairs, they are also known as valuable intermediates in organic transformations.…”