Poly(thioether-ester) nanoparticles entrapping clove oil for antioxidant activity improvement

ZnO and quercetin encapsulated nanoparticles for sun protection obtained by miniemulsion polymerization using alternative co-stabilizers

“…Antioxidant activity of free and encapsulated quercetin and green coffee oil was measured based on its ability to transfer electrons or hydrogen atom to 2,2-diphenyl-1-picryl hydrazyl (DPPH·), forming a non-radical form 2,2-diphenyl-1-picryl hydrazine (DPPHH) [10]. Briefly, 1 ml of sample at different concentrations was mixed with 400 μl of a solution of DPPH and ethanol (0.3 mM) and placed in a dark room, at 25°C for 60 min.…”

“…Miniemulsion polymerization is an in situ encapsulation technique, where polymer synthesis and encapsulation of the component of interest are performed in a single step [7]. Some authors have evaluated the use of alternative co-stabilizers, such as andiroba oil [8,9]; jojoba oil [8]; clove oil [10]; sunflower seed oil and linoleic acid [11]; linseed oil [9]; argan oil and coconut oil [12], being encapsulated as compounds of interest besides stabilizing the miniemulsion.…”

Encapsulation of clove oil in nanostructured lipid carriers from natural waxes: Preparation, characterization and in vitro evaluation of the cholinesterase enzymes

“…An aliquot of the filtered liquid was adequately diluted in ethanol, transferred to a quartz cuvette and analyzed in the wavelength of 280 nm in a UV-vis spectrophotometer (Hitachi U-1900). The concentration of free clove oil was calculated as previously described elsewhere [35].…”

“…The antioxidant potential of eugenol was extensively studied in the literature [6,10,[13][14][15][16][17], and some studies associating this antioxidant property with acetylcholinesterase inhibition were also reported [3,7]. The acetylcholinesterase (AChE -EC 3.1.1.7) is an enzyme responsible for the termination of cholinergic signaling by hydrolyzing acetylcholine (ACh) and the inhibition of AChE is effective in the treatment and management of Alzheimer's disease, multiple system atrophy, and other conditions [3,7,18].…”

Biobased Ester 2-(10-Undecenoyloxy)ethyl Methacrylate as an Asymmetrical Diene Monomer in Thiol–Ene Polymerization

“…Machado et al 13 used this technique to polymerize dianhydro-D-glucityl diundec-10-enoate, an ester from 10undecenoic acid and isosorbide (2:1), in a thiol−ene polymerization miniemulsion with 1,4-butanedithiol (1,4-BDT) initiated by α,α′-azoisobutyronitrile to obtain nanoparticles that showed biocompatibility in murine fibroblasts and uterine colon cancer. In subsequent works, Meneses et al 34 used this methodology to entrap clove oil, obtaining antioxidant activity, and Hoelscher et al 35 performed enzymatic degradation of these nanoparticles, showing the effect of the hydrolysis of the ester bond. Cardoso et al 14 performed thiol−ene polymerizations in miniemulsions using 1,4-BDT and a diene ester from 10undecenoic acid and 1,3-propanediol, 1,3-propylene diundec-10-enoate, to produce poly(thioether ester) nanoparticles, which showed biocompatibility in murine fibroblasts and human cervix epitheloid carcinoma cells.…”