Polycaprolactone-based shape memory polymeric nanocomposites for biomedical applications

Hada, Vaishnavi; Hashmi, S. A. R.; Mili, Medha; Gorhe, Nikhil Rajendra; Sagiri, Sai Sateesh; Pal, Kunal; Chawdhary, Rashmi; Khan, Manal M; Naik, Ajay; Prashant, N.; Srivastava, Avanish Kumar; Verma, Sanjeev Kumar

doi:10.1016/b978-0-12-822858-6.00014-5

Cited by 5 publications

(5 citation statements)

References 88 publications

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“…As one of the most promising intelligent materials, SMPNs can stabilize their temporary shape and return to their original shape when exposed to external stimuli such as heat, light, pH, and magnetism. [1][2][3][4][5] Therefore, SMPNs have attracted increasing attention and have shown promise of application in many fields, such as drug delivery, diagnostics, smart optical systems, biosensors, smart textiles, and artificial tissue engineering.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2,3 ] Generally, SMAs are separated into two sets relative to the stimulus strategies (thermoresponsive SMAs triggered only thermally and magneto‐responsive SMAs triggered by static or variable magnetic field). [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

“…[2,3] Generally, SMAs are separated into two sets relative to the stimulus strategies (thermoresponsive SMAs triggered only thermally and magneto-responsive SMAs triggered by static or variable magnetic field). [4] Being a form of smart materials exhibiting peculiar characteristics, SMAs are versatily utilized in varying fields, especially in medically and industrially affiliated fields, including fire security systems, dental wires, helicopter blades, as well as arterial stents. [1][2][3][4][5] From the inception of SMPs in the 80's, SMPs provide more stimulation strategies, including water immersion, electrical current, heating, alternating magnetic fields, as well as light exposure, [6][7][8] resulting from the underlying broad extensibility because of the intrinsic elastic prone polymeric architectures.…”

Section: Introductionmentioning

confidence: 99%

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Multifunctional properties optimization and stimuli‐responsivity of shape memory polymeric nanoarchitectures and applications

Idumah

2023

Polymer Engineering & Sci

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As a result of nanotechnological advancement, parameters inducing flaws in shape memory polymers (SMP), such as weak mechanical properties, low electrical, and thermal conductivities, and so on, were mitigated through the inclusion of a versatile range of nanomaterials such as montmorillonites, carbon nanotubes, graphene and derivatives, cellulose nanocrystals, carbon nanofibers, and so on, thereby forming shape memory polymeric nanoarchitectures (SMPNs). Hence, this work elucidates most recently emerging advancements on multifunctional SMPNs filled by differing nanoparticulates. Varying multifunctional SMPNs exhibit responsivity to varying forms of stimulation strategies, including thermal responsivity, electroactivated, alternating magnetic field responsivity, light sensitivity, and water induced SMPs. Therefore, this article presents very recently emerging advancements in the construction, characterization, properties, and multifunctional applications of stimuliresponsive SMPNs, with special emphasis on functional and stimuli-responsive SMPNs. Furthermore, important functions of SMPNs such as stimuli-memory effect and self-mending abilities, as well as prospective strategies for future progress of these materials are highlighted.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Multifunctional properties optimization and stimuli‐responsivity of shape memory polymeric nanoarchitectures and applications

Idumah

2023

Polymer Engineering & Sci

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“…Subsequent dissolution of PLA in blood eliminates the need for removal or complications from long-term implantation. Similarly, the predictable biodegradation kinetics, ease of fabrication and biocompatibility of PCL make it ideal for tissue engineering scaffolds [81]. Polyhydroxyalkanoates have also received considerable medical attention; for example, poly-3-hydroxybutyrate slowly hydrolyses to (R)-3-hydroxybutyric acid, which naturally occurs in blood at concentrations of 0.3 -0.13 mM, making it an attractive option for biodegradable drug delivery systems as well as sutures [82,83].…”

Section: Introductionmentioning

confidence: 99%

Advances in continuous polymer analysis in flow with application towards biopolymers

et al. 2023

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Biopolymers, polymers derived from renewable biomass sources, have gained increasing attention in recent years due to their potential to replace traditional petroleum-based polymers in a range of applications. Among the many advantages of biopolymers can be included their biocompatibility, excellent mechanical properties, and availability from renewable feedstock. However, the development of biopolymers has been limited by a lack of understanding of their properties and processing behaviours. Continuous analysis techniques have the potential to hasten progress in this area by providing real-time insights into the properties and processing of biopolymers. Significant research in polymer chemistry has focused on petroleum-derived polymers and has thus provided a wealth of synthetic and analytical methodologies which may be applied to the biopolymer field. Of particular note is the application of flow technology in polymer science and its implications for accelerating progress towards more sustainable and environmentally friendly alternatives to traditional petroleum-based polymers. In this mini review we have outlined several of the most prominent use cases for biopolymers along with the current state-of-the art in continuous analysis of polymers in flow, including defining and differentiating atline, inline, online and offline analysis. We have found several examples for continuous flow analysis which have direct application to the biopolymer field, and we demonstrate an atline continuous polymer analysis method using size exclusion chromatography. Graphical abstract

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“…Stimuli-responsive polymeric matrices remarkably vary their attributes including phase separation, shape, mechanical behaviors, surface, permeability, optically inclined properties, as well as electrical attributes when subjected to small changes in environmental parameters relative to electric field, temperature, pH, glucose, light, electrical field, magnetic field, sonic field, ions, solvent, as well as enzymes as depicted in Figure 1. [1][2][3][4][5][6][7] Shape memory polymers (SMPs) are a class of stimuli responsive polymeric matrices, capable of recovering their original (or permanent) shape when subjected to external stimuli. [8][9][10][11][12][13][14] SMPs are capable of versatile utilization in varying areas including biomedical gadgets, textiles, aerospace, energy, electronic engineering, bionics engineering, civil engineering, as well as household items.…”

Section: Introductionmentioning

confidence: 99%

Construction, characterization, properties and multifunctional applications of stimuli-responsive shape memory polymeric nanoarchitectures: a review

Idumah

Odera

Ezeani

et al. 2023

Polymer-Plastics Technology and Materials

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Due to the advent of nanotechnology, deficiencies and limitations inherent in stimuli-responsive shape memory polymeric matrices (SMP), have been effectively mitigated, through the inclusion of a versatile range of organic or inorganic nanoparticulates within the confines of SMP matrice/s. This phenomenon has resulted in the emergence of shape-memory polymeric nanoarchitectures (SMPNs) possessing enhanced and outstanding properties, when compared with the pristine SMP, and this has subsequently enlarged their scope of applications (civil engineering, biomedical gadgets, aerospace, bionics engineering, energy, electronic engineering, household products, and textile engineering). Furthermore, SMPNs enhances athermal stimuli-activities including electroactivity, magneto-activity, water-activity, and photo-activity, as well as shape memory effect (SME) including multiple-shape memory effect (MSME), spatial shape memory effect (SSME), as well as dual-route shape memory effect (DRSME). This elucidation is essential and imperative at this time to enlighten the polymeric universe on new advancements in fabrication, features and applications of stimuli responsive SMPNs. Therefore, this paper, presents, very recently emerging advancements, in construction, characterization, properties and multifunctional applications of stimuli-responsive SMPNs with special emphasis on carbon nanotubes (CNT), carbon nanofibers (CNF), cellulose nanocrystals, and nanoclay reinforced SMPNs.

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Polycaprolactone-based shape memory polymeric nanocomposites for biomedical applications

Cited by 5 publications

References 88 publications

Multifunctional properties optimization and stimuli‐responsivity of shape memory polymeric nanoarchitectures and applications

Multifunctional properties optimization and stimuli‐responsivity of shape memory polymeric nanoarchitectures and applications

Advances in continuous polymer analysis in flow with application towards biopolymers

Construction, characterization, properties and multifunctional applications of stimuli-responsive shape memory polymeric nanoarchitectures: a review

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