Polycystic Kidney Disease and Seatbelts

Amend, W; Galen, M. A.

doi:10.7326/0003-4819-79-2-287_1

Cited by 10 publications

(4 citation statements)

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“…The kidneys are located in the retroperitoneal space and are protected by the back musculature, the lower ribs, and the perinephric fat, thus, significant force and major trauma is usually required to injure the kidney [ 4 , 5 ]. However, in the presence of pre-existing renal lesions, trivial trauma can result in blunt renal injury and ensuing symptoms can get out of proportion to the type of injury in these cases [ 6 ]. This topic is scantly described in the literature and management guidelines of such patients are still lacking.…”

Section: Introductionmentioning

confidence: 99%

Autosomal dominant polycystic kidney disease and minimal trauma: medical review and case report

et al. 2018

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BackgroundBlunt abdominal trauma in the setting of polycystic kidney disease is still scantly described in the literature and management guidelines of such patients are not well-established.Case presentationThe authors herein present a case of hypovolemic shock secondary to segmental renal artery bleed in a 75-year-old man with polycystic kidney disease after minimal blunt abdominal trauma, who underwent successful selective arterial embolization, and provide a thorough review of similar cases in the literature, while shedding the light on important considerations when dealing with such patients.ConclusionsIt is important to suspect renal injury in patients with pre-existing renal lesions irrespective of the mechanism of injury; and, vice-versa to suspect an underlying abnormality in patients with a clinical deterioration that’s out of proportion to the mechanism of injury.Electronic supplementary materialThe online version of this article (10.1186/s12873-018-0192-3) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

Autosomal dominant polycystic kidney disease and minimal trauma: medical review and case report

et al. 2018

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“…Enlarged kidneys as a result of cysts increase the risk that seat belts may cause injury (75). Patients with greatly enlarged polycystic kidneys complain that seat belts increase pain in normal use.…”

Section: Cosmetic Deformation Of the Abdomenmentioning

confidence: 99%

Volume Progression in Autosomal Dominant Polycystic Kidney Disease

Grantham

Chapman

Torres

2006

Clinical Journal of the American Society of Nephrology

270

212

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Autosomal dominant polycystic kidney disease (PKD) is a hereditary condition characterized by the progressive enlargement of innumerable renal cysts that contribute to life-altering morbidity early in the course of the disease. Evidence indicates that the rate of increase in kidney volume can be reliably measured by magnetic resonance or computed tomography imaging, thus providing objective means to judge the effectiveness of therapies that are targeted to the aberrant growth of renal tubules. It is now possible, therefore, to monitor the effectiveness of potential therapies on the signature abnormality in autosomal dominant PKD before irreversible damage has been done by the cysts. Evidence accumulated from human cross-sectional and longitudinal studies and longitudinal studies of PKD models in animals provide strong support for the view that reducing the rate of kidney volume enlargement will ameliorate the late-stage development of renal insufficiency.

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“…In some cases, however, patients will be unusually susceptible to abdominal trauma. Cyst rupture has been caused by seat belt constraints in automobiles and airplanes (21,22). In male patients with massive kidneys, we recommend the use of suspenders rather than constrictive belts.…”

Section: Physical Activity and Lifestylementioning

confidence: 99%