Polyelectrolyte multilayers functionalized by a synthetic analogue of an anti-inflammatory peptide, α-MSH, for coating a tracheal prosthesis

Schultz, P.; Vautier, Dominique; Richert, Ludovic; Jessel, Nadia; Haïkel, Youssef; Schaaf, Pierre; Voegel, Jean‐Claude; Ogier, Joëlle; Debry, Christian

doi:10.1016/j.biomaterials.2004.06.049

Cited by 108 publications

(107 citation statements)

References 40 publications

Supporting

Mentioning

107

Contrasting

Order By: Relevance

“…For example, synthetic polyelectrolytes such as polyethyleneimine (PEI), poly(sodium 4-styrene sulfonate) (PSS), poly(allylamine hydrochloride) (PAH), poly(l-glutamic acid) (PGA) and poly(l-lysine) (PLL) were used in combination to create the {PEI-(PSS-PAH)2-(PGA-PLL)n} PEM coating on the surface of oral prostheses in order to increase wettability of the prosthesis bases 16) . The combination of polyelectrolytes such as PLL, PGA and functionalized-PGA were used with a synthetic analogue of natural peptide, -melanocyte-stimulation hormone (-MSH), to fabricate a {PLL/(PGA/PLL)4/PGA-MSH} PEM film with antiinflammatory properties on the surface of tracheal prostheses 17) . In addition, fabricating PEM films, PEI-(PSS-PAH)2-(PGA-PLL)-(PGA-defensin-PLL)n, has been introduced on implantable biomaterials in order to obtain anti-microbial properties 18) .…”

Section: Introductionmentioning

confidence: 99%

Differentiation of MC3T3-E1 on poly(4-styrenesulfonic acid-co-maleic acid)sodium salt-coated films

et al. 2011

View full text Add to dashboard Cite

Polyelectrolyte multilayer (PEM) film can modify the surface properties of materials to improve cellular responses. In this study poly(diallyldimethylammonium chloride) (PDADMAC), poly(sodium 4-styrene sulfonate) (PSS) and poly(4-styrenesulfonic acid-comaleic acid) sodium salt (PSS-co-MA) were assembled into PEM {(PDADMAC/PSS)4/PDADMAC+PSS-co-MA} film on glass surfaces and its ability on affecting osteoblast functions were examined. PSS-co-MA film showed an increase roughness and more wettable surface as compared to glass. When the osteoblast cell line, MC3T3-E1, was seeded on the surfaces, no differences were observed in cell attachment or spreading on either PSS-co-MA film or glass at 4-16 hours. However, increases in alkaline phosphatase activity (day-5 and 7) and the expression of osteocalcin mRNA/protein at day-13 were observed. Cells cultured on PSS-co-MA film developed a faster rate of calcium deposition at day-15 compared to control. In conclusion, PSS-co-MA film enhanced osteoblast differentiation and could be used to promote mineralization and improve osseointegration for dental implants.

show abstract

Section: Introductionmentioning

confidence: 99%

Differentiation of MC3T3-E1 on poly(4-styrenesulfonic acid-co-maleic acid)sodium salt-coated films

et al. 2011

View full text Add to dashboard Cite

show abstract

“…The pH of the solution was adjusted as pH 3 with HCl. The Ti disks were immersed and collagen was adsorbed on the Ti surface in the solution at 4 C for 24 h. After adsorption, the disks were removed from the solution remaining layer on it and dried in air. This process followed conventional collagen immobilization technique.…”

Section: Immobilization With Immersion Techniquementioning

confidence: 99%

“…Unless living tissue contact these devices, a crevice between the tissue and device is generated, bacteria invade through the crevice, and infection and/or loosening occurs. [2][3][4] Adhesion of soft tissue to a metal surface is broken by external forces and bacterial toxins because of weak adhesion and the lack of an adhesive structure. 5) To improve the tissue compatibility or cell adhesion of a metal surface, a surface treatment is necessary.…”

Section: Introductionmentioning

confidence: 99%

Effects of pH, Potential, and Deposition Time on the Durability of Collagen Electrodeposited to Titanium

et al. 2011

View full text Add to dashboard Cite

Collagen is expected to work as a bonding agent of soft and hard tissues to solid materials. In this study, the electrodeposition of collagen to a titanium (Ti) surface under various conditions, i.e., the pH of the collagen solution, potential, and electrodeposition time, was performed to understand the optimal electrodeposition conditions for the immobilization of collagen to Ti. The effects of these conditions on the thickness and residual ratio of the collagen layer after shaking in water were evaluated by ellipsometry, scanning probe microscopy, and X-ray photoelectron spectroscopy. Collagen molecules were attracted to Ti cathode and immobilized with high durability by combining electrodeposition conditions, pH 5, alternating potential between À1 V and +1 V vs. SCE with 1 Hz, and 1800 s. The surface of this electrodeposited collagen layer was smooth and uniform maintaining the collagen fibril and natural structure. On the other hand, the collagen layer immobilized by immersion technique in a collagen solution, was rough and irregular. Electrodeposition with alternating potential at pH 5 for 1800 s is a much more appropriate technique to immobilize collagen to Ti than the conventional immersion technique.

show abstract

“…[25][26][27][28][29] In these studies, the macromolecular drug molecules served as both functional drugs and film components. As a coating component, interleukin-12 p70 (IL-12 p70; a key cytokine for cell-mediated immune response), together with a protein carrier (ie, bovine serum albumin), was recently incorporated in polypeptide multilayer nanofilms and it was found that its loading and release were tunable by controlling the number of film layers as well as IL-12 p70 concentration.…”

Section: Dovepressmentioning

confidence: 99%

Advances in polyelectrolyte multilayer nanofilms as tunable drug delivery systems

Jiang

Barnett²,

2009

NSA

View full text Add to dashboard Cite

Polyelectrolyte multilayers functionalized by a synthetic analogue of an anti-inflammatory peptide, α-MSH, for coating a tracheal prosthesis

Cited by 108 publications

References 40 publications

Differentiation of MC3T3-E1 on poly(4-styrenesulfonic acid-co-maleic acid)sodium salt-coated films

Differentiation of MC3T3-E1 on poly(4-styrenesulfonic acid-co-maleic acid)sodium salt-coated films

Effects of pH, Potential, and Deposition Time on the Durability of Collagen Electrodeposited to Titanium

Advances in polyelectrolyte multilayer nanofilms as tunable drug delivery systems

Contact Info

Product

Resources

About