Polyelectrolytes polarization in nonuniform electric fields

Farahpour, Farnoush; Ejtehadi, Mohammad Reza; Varnik, Fathollah

doi:10.1142/s0129183114410101

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…A question, which could be addressed by additional experiments or computer simulations of the capture mechanism, similar to those of Refs. [27,28].…”

Section: Discussionmentioning

confidence: 99%

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DNA capture into the ClyA nanopore: diffusion-limited versus reaction-limited processes

Nomidis¹,

Hooyberghs²,

Maglia³

et al. 2018

J. Phys.: Condens. Matter

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The capture and translocation of biomolecules through nanometer-scale pores are processes with a potentially large number of applications, and hence they have been intensively studied in recent years. The aim of this paper is to review existing models of the capture process by a nanopore, together with some recent experimental data of short single- and double-stranded DNA captured by the Cytolysin A (ClyA) nanopore. ClyA is a transmembrane protein of bacterial origin which has been recently engineered through site-specific mutations, to allow the translocation of double- and single-stranded DNA. A comparison between theoretical estimations and experiments suggests that for both cases the capture is a reaction-limited process. This is corroborated by the observed salt dependence of the capture rate, which we find to be in quantitative agreement with the theoretical predictions.

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“…A question, which could be addressed by additional experiments or computer simulations of the capture mechanism, similar to those of Refs. [27,28].…”

Section: Discussionmentioning

confidence: 99%

“…Still, it would be desirable to have more insight on the nature of the barrier. A question, which could be addressed by additional experiments or computer simulations of the capture mechanism, similar to those of [29,30].…”

Section: Discussionmentioning

confidence: 99%

DNA capture into the ClyA nanopore: diffusion-limited versus reaction-limited processes

Nomidis¹,

Hooyberghs²,

Maglia³

et al. 2018

J. Phys.: Condens. Matter

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show abstract

Sorting ring polymers by knot type with modulated nanochannels

2017

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In this theoretical study we discuss a novel method for sorting ring polymers according to their topological, knotted state. The proposed approach harnesses the rich dynamical behaviour of polymers confined inside spatially-modulated nanochannels. The longitudinal mobility of the rings is shown to have two key properties that are ideally suited for knot sorting. First, at fixed topology, the mobility has an intriguing oscillatory dependence on chain length. Second, the mobility ranking of different knot types is inverted upon increasing the chain length. We show that this complex interplay of channel geometry, chain length and topology can be rationalised within a simple theoretical framework based on Fick-Jacobs's diffusive theory. The results and the interpretative scheme ought to be useful for designing microfluidic devices with optimal topological sorting capabilities.

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Polyelectrolytes polarization in nonuniform electric fields

Cited by 2 publications

References 29 publications

DNA capture into the ClyA nanopore: diffusion-limited versus reaction-limited processes

DNA capture into the ClyA nanopore: diffusion-limited versus reaction-limited processes

Sorting ring polymers by knot type with modulated nanochannels

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