2019
DOI: 10.3390/bioengineering6030084
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Polyhydroxybutyrate Production from Natural Gas in A Bubble Column Bioreactor: Simulation Using COMSOL

Abstract: In this study, the simulation of microorganism ability for the production of poly-β-hydroxybutyrate (PHB) from natural gas (as a carbon source) was carried out. Based on the Taguchi algorithm, the optimum situations for PHB production from natural gas in the columnar bubble reactor with 30 cm length and 1.5 cm diameter at a temperature of 32 °C was evaluated. So, the volume ratio of air to methane of 50:50 was calculated. The simulation was carried out by COMSOL software with two-dimensional symmetric mode. Ma… Show more

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Cited by 9 publications
(6 citation statements)
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“…This work would also significantly facilitate the design and operation of bioreactors devoted to PHA synthesis from biogas. For example, the model and parameters could be implemented in relevant setup to model and optimize PHA production in bioreactors (e.g., bubble column bioreactor 30,31 ) under the feast-famine regime, which has been reported as an ideal operational strategy for PHA accumulation. 32 Moreover, the model and parameters obtained would also favor the practical selection for type II methanotrophs.…”
Section: Model Evaluationsmentioning
confidence: 99%
“…This work would also significantly facilitate the design and operation of bioreactors devoted to PHA synthesis from biogas. For example, the model and parameters could be implemented in relevant setup to model and optimize PHA production in bioreactors (e.g., bubble column bioreactor 30,31 ) under the feast-famine regime, which has been reported as an ideal operational strategy for PHA accumulation. 32 Moreover, the model and parameters obtained would also favor the practical selection for type II methanotrophs.…”
Section: Model Evaluationsmentioning
confidence: 99%
“…A mesh convergence study was performed by running the simulation with several different default mesh configurations of COMSOL, from "Coarser" to "Extremely fine" [17,18]. The results were considered to be independent of mesh resolution when the average temperature and the temperature at the cold point of the pouch between two sequential sets of meshes were less than 1% [19]. The mesh configuration was determined to be "Extra fine" due to the acceptable change.…”
Section: Numerical Simulationmentioning
confidence: 99%
“…The maximum biomass concentration amounted to 1.63 g/L, which shows a difference of only 10% in comparison to elaborated experimental results. Moreover, the impact of the inlet gas rate on product concentration and gas hold up was studied, and the simulated results were compared to experimental data; a high prediction performance of the simulation was demonstrated by a deviation of less than 20% [18]. Donya Kamravamanesh and colleagues reviewed PHA production from another gaseous substrate, namely CO 2 -based, solar-driven PHA production by cyanobacteria.…”
Section: Individual Contributionsmentioning
confidence: 99%