Polymer/Ceramic Nanocomposite Fibers in Bone Tissue Engineering

Sowmya, S; Mathivanan, Nirmal; Chandramouli, Arthi; Jayakumar, R.

doi:10.1007/12_2023_145

Cited by 4 publications

(4 citation statements)

References 102 publications

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“…Wong et al [147] and Chan et al [148] reviewed the thermal-flammability and mechanical properties of wollastonite-filled thermoplastic composites. Other important applications of wollastonite composites include the bioengineering [149].…”

Section: Categorymentioning

confidence: 99%

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Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Thapliyal,

Verma,

Sen

et al. 2023

J. Compos. Sci.

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This comprehensive review explores the multifaceted world of natural fiber applications within the domain of composite materials. Natural fibers are meticulously examined in detail, considering their diverse origins, which encompass plant-derived fibers (cellulose-based), animal-derived fibers (protein-based), and even mineral-derived variations. This review conducts a profound analysis, not only scrutinizing their chemical compositions, intricate structures, and inherent physical properties but also highlighting their wide-ranging applications across various industries. The investigation extends to composites utilizing mineral or polymer matrices, delving into their synergistic interplay and the resulting material properties. Furthermore, this review does not limit itself to the intrinsic attributes of natural fibers but ventures into the realm of innovative enhancements. The exploration encompasses the augmentation of composites through the integration of natural fibers, including the incorporation of nano-fillers, offering a compelling avenue for further research and technological development. In conclusion, this review synthesizes a comprehensive understanding of the pivotal role of natural fibers in the realm of composite materials. It brings together insights from their diverse origins, intrinsic properties, and practical applications across sectors. As the final curtain is drawn, the discourse transcends the present to outline the trajectories of future work in the dynamic arena of natural fiber composites, shedding light on emerging trends that promise to shape the course of scientific and industrial advancements.

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Section: Categorymentioning

confidence: 99%

“…Important applications of mineral nanocomposites such as wollastonite include bioengineering [149]. A detailed review of mineral nanocomposites is given in [150].…”

Section: Animal and Mineral Fibers And Nanocompositesmentioning

confidence: 99%

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Thapliyal,

Verma,

Sen

et al. 2023

J. Compos. Sci.

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“…Based on their composition, biomaterials can be classified as bioceramics, polymers, metals, or composites [10]. Ceramics offer numerous advantages, including similarity to the mineralogical composition of native bone and osteoconductive properties; however, their application is limited due to their brittle nature and difficulty in processing [11]. When it comes to polymer-based scaffolds, they can be procured from both synthetic and natural sources.…”

Section: Introductionmentioning

confidence: 99%

“…The electrospinning is performed using a simple protocol where a polymer solution is loaded into a syringe and subjected to an applied voltage; when the supplied electric potential overcomes the surface tension, the droplet extends to form fibers that get collected on the collector as non-woven fiber as it dries. The produced NFs exhibit high surface-area-to-volume ratio, high porosity, and intrinsic mechanical properties and mimic the ECM in vivo [11,21]. In this review, we predominantly discuss electrospun CT/CS NFs, their derivatives, applications, and therapeutic prospects in the field of BTE.…”

Section: Introductionmentioning

confidence: 99%

Recent Advancements in Electrospun Chitin and Chitosan Nanofibers for Bone Tissue Engineering Applications

Ganesh,

Anushikaa,

Swetha Victoria

et al. 2023

JFB

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Treatment of large segmental bone loss caused by fractures, osteomyelitis, and non-union results in expenses of around USD 300,000 per case. Moreover, the worst-case scenario results in amputation in 10% to 14.5% of cases. Biomaterials, cells, and regulatory elements are employed in bone tissue engineering (BTE) to create biosynthetic bone grafts with effective functionalization that can aid in the restoration of such fractured bones, preventing amputation and alleviating expenses. Chitin (CT) and chitosan (CS) are two of the most prevalent natural biopolymers utilized in the fields of biomaterials and BTE. To offer the structural and biochemical cues for augmenting bone formation, CT and CS can be employed alone or in combination with other biomaterials in the form of nanofibers (NFs). When compared with several fabrication methods available to produce scaffolds, electrospinning is regarded as superior since it enables the development of nanostructured scaffolds utilizing biopolymers. Electrospun nanofibers (ENFs) offer unique characteristics, including morphological resemblance to the extracellular matrix, high surface-area-to-volume ratio, permeability, porosity, and stability. This review elaborates on the recent strategies employed utilizing CT and CS ENFs and their biocomposites in BTE. We also summarize their implementation in supporting and delivering an osteogenic response to treat critical bone defects and their perspectives on rejuvenation. The CT- and CS-based ENF composite biomaterials show promise as potential constructions for bone tissue creation.

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Electrospinning of Carboxymethyl Chitosan Derivatives-Based Nanofibers and Its Applications

Arthi,

Jayakumar

2023

Advances in Polymer Science

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Polymer/Ceramic Nanocomposite Fibers in Bone Tissue Engineering

Cited by 4 publications

References 102 publications

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Recent Advancements in Electrospun Chitin and Chitosan Nanofibers for Bone Tissue Engineering Applications

Electrospinning of Carboxymethyl Chitosan Derivatives-Based Nanofibers and Its Applications

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