2023
DOI: 10.3390/jfb14050288
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Recent Advancements in Electrospun Chitin and Chitosan Nanofibers for Bone Tissue Engineering Applications

S Shree Ganesh,
Ramprasad Anushikaa,
Venkadesan Sri Swetha Victoria
et al.

Abstract: Treatment of large segmental bone loss caused by fractures, osteomyelitis, and non-union results in expenses of around USD 300,000 per case. Moreover, the worst-case scenario results in amputation in 10% to 14.5% of cases. Biomaterials, cells, and regulatory elements are employed in bone tissue engineering (BTE) to create biosynthetic bone grafts with effective functionalization that can aid in the restoration of such fractured bones, preventing amputation and alleviating expenses. Chitin (CT) and chitosan (CS… Show more

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Cited by 14 publications
(4 citation statements)
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“…4(a) ), single-needle ES 52 ( Fig. 4(b) ), coaxial ES 53,54 ( Fig. 4(c) ), and multineedle ES 55,56 ( Fig.…”
Section: Introductionmentioning
confidence: 99%
“…4(a) ), single-needle ES 52 ( Fig. 4(b) ), coaxial ES 53,54 ( Fig. 4(c) ), and multineedle ES 55,56 ( Fig.…”
Section: Introductionmentioning
confidence: 99%
“…By contrast, suitably adjusted conditions for regeneration from chitin solutions/gels has resulted in self-assembled ChNFs according to the bottom-up procedure (Figure 2a) [29,30]. Electrospinning has also been used for the self-assembly of ChNFs from chitin solutions [31,32].…”
Section: Introductionmentioning
confidence: 99%
“…By contrast, suitably adjusted conditions for regeneration from chitin solutions/gels has resulted in self-assembled ChNFs according to the bottom-up procedure (Figure 2a) [29,30]. Electrospinning has also been used for the self-assembly of ChNFs from chitin solutions [31,32]. Furthermore, nanocomposite materials derived from polymeric components have endless applications, ranging from low-cost household products to high-value industrial production entities.…”
Section: Introductionmentioning
confidence: 99%
“…Chelating polymers have attracted attention in the adsorption of heavy metal ions from aqueous phases and environmental remediation. Chitosan is a natural linear polysaccharide composed of (1,4)-2-amino-2-deoxy-β-D-glucan and can be fabricated by a partial chitin deacetylation process [14].…”
Section: Introductionmentioning
confidence: 99%