Polymer-Modified Silica Adsorbent with Reversed-Phase and Weak Cation-Exchange Groups

Hayrapetyan, Sergey S.; Khachatryan, H. G.

doi:10.1365/s10337-004-0457-8

Cited by 4 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Depending on the molecular structure of the bonded material, H-bonding, p-p or hydrophobic interactions may also be present in addition to the ion-exchange mechanism. A number of previous investigations have utilized the multi-modal capabilities of carboxylic acid phases on silica for chiral separations [2][3][4] as well as a variety of ionic/polar organic compounds [5,6].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and HPLC evaluation of carboxylic acid phases on a hydride surface

Pesek¹,

Matyska

Gangakhedkar

et al. 2006

J of Separation Science

View full text Add to dashboard Cite

Three organic moieties containing carboxylic acid functional groups are attached to a particulate silica surface through silanization/hydrosilation. Two compounds (undecylenic acid and 10-undecynoic acid) have 11 carbon chains and the other is a five-carbon acid (pentenoic acid). Bonding is confirmed through carbon elemental analysis, diffuse reflectance infrared fourier transform spectroscopy, and carbon-13 and silicon-29 CP-MAS NMR spectroscopy. The bonded phases are tested by HPLC using PTH amino acids, nucleic acids, theophylline-related compounds, anilines, benzoic acid compounds, choline, and tobramycin. The latter two compounds are used to investigate the aqueous normal phase properties of the three bonded materials.

show abstract