Polymer nanofiber thin films for biosensor applications

Kwoun, S.J.; Lec, R.M.; Han, Bing; Ko, Frank

doi:10.1109/nebc.2001.924694

Cited by 11 publications

(7 citation statements)

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“…The associate editor coordinating the review of this paper and approving it for publication was Dr. Richard Fair. chemical warfare agents, and biological species [1]- [4]. They are used mostly to detect the adsorption or attachment of protein molecules [5], cells [6], bacteria [7], or the immunological properties of cytokines conjugated to organisms on the plate surface of two-port IDTs [8].…”

Section: Introductionmentioning

confidence: 99%

“…There has been a notable development in biosensing detections in recent years, such as the quartz crystal microbalance (QCM) [9], [10], the thickness shear mode (TSM) [1], the acoustic plate mode (APM) [11], the flexural plate wave (FPW) [12]- [16], the love mode [17], the shear horizontal acoustic plate mode (SH-APM) [18], and the surface acoustic wave (SAW) [19]. In general, the FPW has a higher sensitivity with the loading changes at lower operating frequencies among all these detecting methods [20], [21].…”

Section: Introductionmentioning

confidence: 99%

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Phase Detection of the Two-Port FPW Sensor for Biosensing

et al. 2008

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This study reports the phase detection of the two-port flexural plate wave (FPW) sensor for designing and integrating the miniature system and provides a comprehensive methodology for portable using in the biosensor applications of severe acute respiratory syndrome coronavirus (SARS-CoV). The miniature system mainly utilizes the concept of the frequency divider that involves a divider, a time-based oscillator and a gate to reduce the high frequency, and the FPW sensor is fabricated using microelectromechanical systems (MEMS) technologies for producing a potable biosensing detector. The results demonstrate that the insertion loss decreased about 1 15% dB/ C, and the phase delay was about 2.05 /(1000 cP). The phaseshift resolution was about 10 mV per degree, and the original frequency of 4.2 MHz was divided by 100 to reduce the frequency to 42 kHz. The SARS-CoV could be detected via the S protein binds to the human angiotensin-converting enzyme 2 (hACE2) as a functional receptor, which would cause the phase delay due to the combining of the antibody with the antigen. Therefore, the feasibility studies provide the information that phase detection is an appropriate low-cost technology via frequency divider for fabricating of the miniature biosensors.Index Terms-Biosensing, flexural plate wave, integrated system, phase detection, readout concept, severe acute respiratory syndrome coronavirus (SARS-CoV).

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Phase Detection of the Two-Port FPW Sensor for Biosensing

et al. 2008

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“…Fiber diameter and pore size are the two key factors that affect the performance of the fiber mat. [29][30][31][32][33] By correlating fiber diameter with pore size, we found that the effects of sonic vibration treatment on fiber diameter and pore size follow different tendencies, as shown in Figure 5. Sonic vibration has stronger effects on both the fiber diameter and the pore size.…”

Section: Effect On Pore Structurementioning

confidence: 99%

The effect of sonic vibration on electrospun fiber mats

Qiang

Wan

et al. 2018

Journal of Low Frequency Noise, Vibration and Active Control

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Electrospun nanofibers have shown great potential in wide applications such as energy, filtration, medical devices, and sensors. For all these applications, fiber morphology, fiber diameter and pore size of electrospun fiber mat play critical roles in determining the performance of the final products. Research has proved that sonic vibration can dramatically improve the electrospinnability of polymer solutions and subsequently the resultant fiber properties. In this work, the effects of sonic vibration on fiber morphology as well as fiber diameter and the pore structures of electrospun polyacrylonitrile fiber mat were investigated. The relationships between sonic vibration and fiber diameter, and pore size of the electrospun fiber mats were also studied.

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“…Poly-Lactic Acid-co-Glycolic Acid nanofibers have been deposited on thickness shear mode piezoelectric sensors [72,73]. Feng et al have developed a formaldehyde sensor using a molecularly imprinted polymer as the recognition element and QCM as the sensor [74].…”

Section: Polymer-based Sensorsmentioning

confidence: 99%

Microfabricated Formaldehyde Gas Sensors

Flueckiger

Cheung

2009

Sensors

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Formaldehyde is a volatile organic compound that is widely used in textiles, paper, wood composites, and household materials. Formaldehyde will continuously outgas from manufactured wood products such as furniture, with adverse health effects resulting from prolonged low-level exposure. New, microfabricated sensors for formaldehyde have been developed to meet the need for portable, low-power gas detection. This paper reviews recent work including silicon microhotplates for metal oxide-based detection, enzyme-based electrochemical sensors, and nanowire-based sensors. This paper also investigates the promise of polymer-based sensors for low-temperature, low-power operation.

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Polymer nanofiber thin films for biosensor applications

Cited by 11 publications

References 1 publication

Phase Detection of the Two-Port FPW Sensor for Biosensing

Phase Detection of the Two-Port FPW Sensor for Biosensing

The effect of sonic vibration on electrospun fiber mats

Microfabricated Formaldehyde Gas Sensors

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