Polymeric Blends with Biopolymers

Heeres, Hero J.; Mastrigt, Frank van; Picchioni, Francesco

doi:10.1002/9783527652457.ch6

Cited by 3 publications

(4 citation statements)

References 277 publications

(96 reference statements)

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“…These materials have attracted researchers' interest due to their ability to modify the properties of other materials for particular applications. Earlier researchers obtained polymer blends from natural materials [125][126][127]. This technique is straightforward, fast, and cost-saving compared to other tedious and time-consuming methods.…”

Section: Polymer Blendingmentioning

confidence: 99%

“…The naturally occurring biopolymer containing the different functional groups can be used to modify the PPSU hydrophilicity and surface structures. There is growing interest in polymer technology to use biopolymers as modifiers or as additives due to their biocompatibility, nontoxicity, and antimicrobial properties [127,[154][155][156][157][158]. In recent studies by Alam et al [74] the PPSU polymer blended with naturally occurring carrageenan biopolymer as an additive facilitated improvement in membrane porosity.…”

Section: Polyphenylsulfone Blended With the Biopolymermentioning

confidence: 99%

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Recent Advancements in Polyphenylsulfone Membrane Modification Methods for Separation Applications

2022

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Polyphenylsulfone (PPSU) membranes are of fundamental importance for many applications such as water treatment, gas separation, energy, electronics, and biomedicine, due to their low cost, controlled crystallinity, chemical, thermal, and mechanical stability. Numerous research studies have shown that modifying surface properties of PPSU membranes influences their stability and functionality. Therefore, the modification of the PPSU membrane surface is a pressing issue for both research and industrial communities. In this review, various surface modification methods and processes along with their mechanisms and performance are considered starting from 2002. There are three main approaches to the modification of PPSU membranes. The first one is bulk modifications, and it includes functional groups inclusion via sulfonation, amination, and chloromethylation. The second is blending with polymer (for instance, blending nanomaterials and biopolymers). Finally, the third one deals with physical and chemical surface modifications. Obviously, each method has its own limitations and advantages that are outlined below. Generally speaking, modified PPSU membranes demonstrate improved physical and chemical properties and enhanced performance. The advancements in PPSU modification have opened the door for the advance of membrane technology and multiple prospective applications.

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Section: Polymer Blendingmentioning

confidence: 99%

Section: Polyphenylsulfone Blended With the Biopolymermentioning

confidence: 99%

Recent Advancements in Polyphenylsulfone Membrane Modification Methods for Separation Applications

2022

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“…Among them are protein-based biocomposites consisting of proteins or protein blends and additives or fillers that are incorporated into the protein (blend) matrix. Depending on the particle size of the incorporated additives, bionanocomposites, biomicrocomposites and biomacrocomposites can be distinguished [33,34,35]. Various embedded organic and inorganic fillers in the form of loose or coherent particles or fibers contribute to the enhancement of physical properties and to the reduction of costs of protein-based biocomposites [35,36].…”

Section: Protein-based Biocomposites As Drug Delivery Systemsmentioning

confidence: 99%

New Aspects in the Formulation of Drugs Based on Three Case Studies

2016

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Abstract:The improvement of pharmaceutical dosage forms, such as tablets, towards drug delivery control and cost efficiency is of great importance in formulation technologies. Here, three examples: in situ coating, freeze casting and protein-based biocomposites are presented that address the above mentioned issues and contribute to further developments in formulation technologies. The in situ coating increases the economic efficiency by saving process steps in comparison to a conventional tableting process and provides a crystalline coating for a tailorable drug delivery rate. The freeze casting allows the control over the surface area of a drug delivery system (DDS) by providing different numbers and sizes of pores, which in conjunction with adequate additives offer an efficient instrument for drug delivery control, especially by accelerating the dissolution effect. Protein-based biocomposites are attractive materials for biomedical and pharmaceutical applications that can be applied as a polymeric DDS. They inherently combine degradability in vivo and in vitro, show a good biocompatibility, offer sites of adhesion for cells and may additionally be used to release embedded bioactive molecules. Here, a new approach regarding the incorporation of crystalline active pharmaceutical ingredients (API) into a protein matrix in one process step is presented. All three presented techniques mark decisive progress towards tailor-made drug delivery systems with respect to function, economic efficiency and the generation of additional values.

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“…In this article, the authors have mainly focused on chitosan-based polymer blends in drug delivery [23]. It is widely used as a carrier in drug delivery, orthopedics, cell delivery systems, wound healing, bone healing, and ophthalmology as it can increase the func- There are various types of polymer blends, including thermoplastic-thermoplastic, rubber-thermoplastic, thermoplastic-thermosetting, rubber-thermosetting, and polymer filler blends [17,18]. Polymer blending has various applications (Figure 2) [14,19].…”

Section: Introductionmentioning

confidence: 99%

Chitosan-Based Polymer Blends for Drug Delivery Systems

et al. 2023

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Polymers have been widely used for the development of drug delivery systems accommodating the regulated release of therapeutic agents in consistent doses over a long period, cyclic dosing, and the adjustable release of both hydrophobic and hydrophilic drugs. Nowadays, polymer blends are increasingly employed in drug development as they generate more promising results when compared to those of homopolymers. This review article describes the recent research efforts focusing on the utilization of chitosan blends with other polymers in an attempt to enhance the properties of chitosan. Furthermore, the various applications of chitosan blends in drug delivery are thoroughly discussed herein. The literature from the past ten years was collected using various search engines such as ScienceDirect, J-Gate, Google Scholar, PubMed, and research data were compiled according to the various novel carrier systems. Nanocarriers made from chitosan and chitosan derivatives have a positive surface charge, which allows for control of the rate, duration, and location of drug release in the body, and can increase the safety and efficacy of the delivery system. Recently developed nanocarriers using chitosan blends have been shown to be cost-effective, more efficacious, and prolonged release carriers that can be incorporated into suitable dosage forms.

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Polymeric Blends with Biopolymers

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Cited by 3 publications

References 277 publications

Recent Advancements in Polyphenylsulfone Membrane Modification Methods for Separation Applications

Recent Advancements in Polyphenylsulfone Membrane Modification Methods for Separation Applications

New Aspects in the Formulation of Drugs Based on Three Case Studies

Chitosan-Based Polymer Blends for Drug Delivery Systems

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