Polymeric nanocapsules via interfacial cationic photopolymerization in miniemulsion

Artusio, Fiora; Bazzano, Marco; Pisano, Roberto; Coulon, Pierre‐Eugène; Rizza, Giancarlo; Schiller, Tara L.; Sangermano, Marco

doi:10.1016/j.polymer.2018.02.019

Cited by 21 publications

(13 citation statements)

References 23 publications

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“…The nanocapsules showed a rapid drug release at pH 6.5 responding to the pH sensitive property of the polymer. In addition, other chemical reactions were also applied to preform polymeric nanocapsules by emulsion–coacervation method, such sonochemical reaction [ 66 , 107 ] or photopolymerization [ 108 , 109 ]. The studies of polymeric nanocapsules formulated by emulsion–coacervation methods in recent five years are summarized in Table 3 .…”

Section: Current Status Of Nanocapsules: Materials and Formulationmentioning

confidence: 99%

Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

et al. 2020

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Polymer-based nanocapsules have been widely studied as a potential drug delivery system in recent years. Nanocapsules—as one of kind nanoparticle—provide a unique nanostructure, consisting of a liquid/solid core with a polymeric shell. This is of increasing interest in drug delivery applications. In this review, nanocapsules delivery systems studied in last decade are reviewed, along with nanocapsule formulation, characterizations of physical/chemical/biologic properties and applications. Furthermore, the challenges and opportunities of nanocapsules applications are also proposed.

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Section: Current Status Of Nanocapsules: Materials and Formulationmentioning

confidence: 99%

Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

et al. 2020

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“…This process can indeed improve the performances of the active material under many points of views. Firstly, the nanomaterial can protect the drug from environmental factors that alter its biological activity [107,109]. Secondly, the encapsulation process allows to control the structure of the core material in order to regulate its interactions with the environment: as an example, such a technique is commonly used to enhance biostability and bioavailability of poorly water-soluble drugs in the blood stream [110].…”

Section: Pharmaceutical Nanocarriers For Dermatological Applicationsmentioning

confidence: 99%

“…In the work of Pereira [123] adapalene (logP = 8.5) loaded PCL nanocapsules were produced and topically applied: the high hydrophobicity of both carrier and drug facilitated diffusion in the SC but no further penetration was observed, making the system suitable for topical administration. Marto et al [70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124] incorporated an anti-inflammatory drug in starch-shelled nanoparticles by emulsion solvent evaporation method. The potential effectiveness of such topical formulation was evaluated both in vitro and in vivo on ra...…”

Section: Pharmaceutical Nanocarriers For Dermatological Applicationsmentioning

confidence: 99%

Bio-Functional Textiles: Combining Pharmaceutical Nanocarriers with Fibrous Materials for Innovative Dermatological Therapies

et al. 2019

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In the field of pharmaceutical technology, significant attention has been paid on exploiting skin as a drug administration route. Considering the structural and chemical complexity of the skin barrier, many research works focused on developing an innovative way to enhance skin drug permeation. In this context, a new class of materials called bio-functional textiles has been developed. Such materials consist of the combination of advanced pharmaceutical carriers with textile materials. Therefore, they own the possibility of providing a wearable platform for continuous and controlled drug release. Notwithstanding the great potential of these materials, their large-scale application still faces some challenges. The present review provides a state-of-the-art perspective on the bio-functional textile technology analyzing the several issues involved. Firstly, the skin physiology, together with the dermatological delivery strategy, is keenly described in order to provide an overview of the problems tackled by bio-functional textiles technology. Secondly, an overview of the main dermatological nanocarriers is provided; thereafter the application of these nanomaterial to textiles is presented. Finally, the bio-functional textile technology is framed in the context of the different dermatological administration strategies; a comparative analysis that also considers how pharmaceutical regulation is conducted.

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“…Emulsion and mini-emulsion polymerization are the most used polymerization technique for the polymeric particles production, but cationic process is strongly inhibited by the presence of water, so in principle it would not be possible to carry a miniemulsion polymerization cationic reaction in aqueous media. We investigated the cationic miniemulsion photopolymerization of triethylene glycol divinyl ether (DVE3) in aqueous phase [2].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Cationic Photopolymerization

Sangermano

2019

J. Photopol. Sci. Technol.

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The paper reports important strategies to overcome limitation of cationic photopolymerization. First, it was possible to run emulsion cationic photopolymerization in water, taking the advantages of hydrophobic droplets of suitable dimension to avoid termination reaction, achieving capsules of about 200 nm. Subsequently a frontal polymerization reaction is used to promote the UV-induced crosslinking process of an epoxy composites via a radical induced cationic frontal polymerization.

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Polymeric nanocapsules via interfacial cationic photopolymerization in miniemulsion

Cited by 21 publications

References 23 publications

Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

Bio-Functional Textiles: Combining Pharmaceutical Nanocarriers with Fibrous Materials for Innovative Dermatological Therapies

Recent Advances in Cationic Photopolymerization

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