Polymerized Structure and Improved Physical and Biochemical Material Properties of Carboxymethyl Dextran-Conjugated Collagen

Development and utilization of a bovine type I collagen microfibril model

“…The resistance of the collagen triple helix to attack by enzymes other than collagenases, and very aggressive proteases, has led to the use of a mild pepsin digestion in the isolation and solublization of collagen in preparation for biomedical and other industrial applications [7]. This treatment partially cleaves the nonhelical telopeptides, interrupting the native crosslinks while leaving the helical domain intact.…”