Polymethylmethacrylate Resins

Geurtsen, Werner

doi:10.1007/978-3-540-77782-3_9

Cited by 11 publications

(7 citation statements)

References 85 publications

(110 reference statements)

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“…However, marginal gaps of Type B were also in accordance with the in vitro data for 3-unit bridges on implants cast from non-precious alloys, which exhibited a mean marginal gap of 80 lm (Oyague et al 2009). The marginal gap for Type A was more than twofold higher than that of Type B but still remained within the range of clinically accepted precision (range of 30 lm to 200 lm) (Christensen 1966;Spiekermann 1986;Geurtsen 1990) and was lower than the mean marginal gaps of crowns on teeth in typical dental offices (Kerschbaum & Porschen 1998;Kerschbaum & Faber 2001).…”

Section: Discussionmentioning

confidence: 69%

Precision of fit and retention force of cast non‐precious‐crowns on standard titanium implant‐abutment with different design and height

Enkling

Ueda

Gholami

et al. 2013

Clinical Oral Implants Res

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Section: Discussionmentioning

confidence: 69%

Precision of fit and retention force of cast non‐precious‐crowns on standard titanium implant‐abutment with different design and height

Enkling

Ueda

Gholami

et al. 2013

Clinical Oral Implants Res

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“…Nonetheless, it is worth emphasising that uncured methacrylate monomers can be absorbed through the skin [12] and cause allergic reactions (e.g. dermatitis) [13,14]. In addition, the toxicity of methacrylate esters is theorized to involve alkylation of critical cellular nucleophiles via Michael addition [15].…”

Section: Discussionmentioning

confidence: 99%

Biocompatibility of 3D Printed Methacrylate for Hearing Aids and Inner Ear Devices

Alifui‐Segbaya¹,

George²

2018

Preprint

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The capacity of 3D printing (3DP) technologies to initiate speedy polymerization of solvent free resins accounts for their utility in the manufacturing of medical devices. Nonetheless, independent biological evaluation of 3D printed materials is recommended due to the unique parameters of the manufacturing process, which can influence their physical, chemical, and biological properties. In this study, E-Shell 450 material indicated for 3DP of hearing aid shells and inner ear devices was examined for biological safety using zebrafish bioassays adapted to OECD fish embryo test. In addition, the proprietary material was characterized for composition using headspace gas-chromatography mass spectrometry (GC-MS). To initiate test, newly fertilized zebrafish eggs were cultured on non-treated and ethanol-treated materials in glass petri dishes with ultrapure water, incubated at 28.5°C and assessed for developmental endpoints of toxicity at 24h interval until 96h. Data confirmed non-treated material was extremely toxic in bioassays within 24h whereas ethanol-treated material showed a relative lower toxicity possibly due to ethanoic-aqueous interactions as observed by GC-MS. With the current influx of 3D printing materials, users are urged to exercise caution. Operators must also take cognizance of the potential toxicity of the chemicals used in 3DP and implement safety measures to limit their exposure.

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“…Nonetheless, uncured methacrylate monomers can be absorbed through the skin [22] and cause allergic reactions (e.g. dermatitis) [23,24]. In addition, the toxicity of methacrylate esters is theorized to involve alkylation of critical cellular nucleophiles via Michael addition [25].…”

Section: Discussionmentioning

confidence: 99%

Biocompatibility of 3D Printed Methacrylate for Hearing Aids and Inner Ear Devices

Alifui‐Segbaya¹,

George²

2018

Preprint

View full text Add to dashboard Cite

The capacity of 3D printing (3DP) technologies to initiate speedy polymerization of solvent free resins accounts for their utility in the manufacturing of medical devices. Nonetheless, independent biological evaluation of 3D printed materials is recommended due to the unique parameters of the manufacturing process, which can influence their physical, chemical, and biological properties. In this study, E-Shell 450 clear methacrylate indicated for 3DP of hearing devices was examined for biological safety using zebrafish bioassays adapted to OECD fish embryo test. In addition, the proprietary material was characterized for composition using headspace gas-chromatography mass spectrometry (GC-MS). To initiate the biological test, newly fertilized zebrafish eggs were cultured on non-treated and ethanol-treated methacrylates in glass petri dishes with ultrapure water, incubated at 28.5°C and assessed for developmental endpoints of toxicity at 24h interval until 96h. Toxicological data indicate non-treated methacrylate is extremely toxic in zebrafish bioassays whereas ethanol-treated counterpart showed a relative lower toxicity possibly due to ethanoic-aqueous interactions as observed by GC-MS. With the current influx of 3D printing materials, users are urged to exercise caution.Operators must also take cognizance of the potential toxicity of the chemicals used in 3DP and implement safety measures to limit their exposure.

show abstract

Polymethylmethacrylate Resins

Cited by 11 publications

References 85 publications

Precision of fit and retention force of cast non‐precious‐crowns on standard titanium implant‐abutment with different design and height

Precision of fit and retention force of cast non‐precious‐crowns on standard titanium implant‐abutment with different design and height

Biocompatibility of 3D Printed Methacrylate for Hearing Aids and Inner Ear Devices

Biocompatibility of 3D Printed Methacrylate for Hearing Aids and Inner Ear Devices

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