Polymorphs of 4-isopropylbenzylidine thiophene-2-carbohydrazide: Crystal growth and density functional theory computations

Synthesis and amide imidic prototropic tautomerization in thiophene-2-carbohydrazide: XRD, DFT/HSA-computation, DNA-docking, TG and isoconversional kineticsviaFWO and KAS models

“…[5][6][7][8][9][10][11][12] Therefore, a huge number of heterocyclic carbohydrazide derivatives have been made available. [6][7][8][9][10][11][12][13][14][15] The prototropic tautomers are compounds that can be interconverted from molecule to another via single proton migration from group to the close neighbor atom. 16 It's known that there is no pure separating line between such tautomers and isomers: tautomer is obviously isomer that transform with a comparatively depressed activation energy <20 kcal mol À1 .…”