Polyp detection rates using magnification with narrow band imaging and white light

Gilani, Nooman; Stipho, Sally; Panetta, James D.; Petre, Sorin; Young, Michele A.; Ramirez, Francisco C.

doi:10.4253/wjge.v7.i5.555

Cited by 3 publications

(2 citation statements)

References 39 publications

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“…A further limitation of the present analysis is that we ended inclusion of studies after 2015 since detailed analysis, author feedback and data homogenization took some time. Another literature search done since 2015 until present revealed 55 citations, and after exclusion of reviews, meta-analyses, secondary studies summarizing previous papers, tandem studies on the entire colon (instead of only right sided tandem) and data available on location, 7 studies remain [37][38][39][40][41][42][43] , which in an additional paper-based meta analysis done by one of us (GGC) did not a higher miss rate in the right colon, rather a trend of a higher miss rate on the left side (see Figure 1…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Right-Sided Location Not Associated With Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies

et al. 2019

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Background & Aims: Interval cancers occur more frequently in the right colon. One reason could be that right-sided adenomas are frequently missed in colonoscopy examinations. We reanalyzed data from tandem colonoscopies to assess adenoma miss rates in relation to location and other factors. Methods:We pooled data from 8 randomized tandem trials, comprising 2218 patients who underwent diagnostic or screening colonoscopies (adenomas detected in 49.8% of subjects). We performed a mixed effects logistic regression with patients as cluster effects with different independent parameters. Factors analyzed included location (left vs right, splenic flexure as cut-off), adenoma size, form, and histologic features. Analyses were controlled for potential confounding factors such as patient sex and age, colonoscopy indication, and bowel cleanliness.Results: Right-side location was not an independent risk factor for missed adenomas (odds ratio [OR] compared with the left side, 0.94; 95% CI, 0.75-1.17). However, compared with adenomas ≤5 mm, the OR for missing adenomas 6-9 mm was 0.62 (95% CI, 0.44-0.87) and the OR for missing adenomas ≥10 mm was 0.51 (95% CI, 0.33-0.77). Compared with pedunculated adenomas, sessile (OR, 1.82; 95% CI, 1.16-2.85) and flat adenomas (OR, 2.47; 95% CI, 1.49-4.10) were more likely to be missed. Histologic features were not significant risk factors for missed adenomas (OR for adenomas with high-grade intraepithelial neoplasia, 0.68; 95% CI, 0.34-1.37 and OR for sessile serrated adenomas, 0.87; 95% CI, 0.47-1.64 compared with low-grade adenomas). Men had a higher number of adenomas per colonoscopy (1.27; 95% CI, 1.21-1.33) than women (0.86; 95% CI, 0.80-0.93). Men were less likely to have missed adenomas than women (OR for missed adenomas in men, 0.73; 95% CI, 0.57-0.94). Conclusions:In an analysis of data from 8 randomized trials, we found that right-side location of an adenoma does not increase its odds for being missed during colonoscopy, but adenoma size and histologic features do increase risk. Further studies are needed to determine why adenomas are more frequently missed during colonoscopies in women than men.

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Section: Accepted Manuscriptmentioning

confidence: 99%

Right-Sided Location Not Associated With Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies

et al. 2019

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“… 47 Six successive RCTs have reflected this and shown no significant increase in ADR with NBI. 48 – 52 , 54 In contrast, a single-centre RCT found higher adenoma miss rates in standard colonoscopy compared to high-definition colonoscopy utilizing NBI (49% versus 27%, p = 0.036). 53 The authors argue that because two different colonoscopes were used in tandem compared to the other previously reported studies – standard colonoscopy followed by another colonoscope with better definition and high contrast – their study was more representative of a true miss rate.…”

Section: Imagingmentioning

confidence: 94%

Can technology increase adenoma detection rate?

Ngu

Rees

2018

Therap Adv Gastroenterol

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Colorectal cancer is the third most common cancer worldwide and the second most common cause of cancer-related death in Europe and North America. Colonoscopy is the gold standard investigation for the colon but is not perfect, and small or flat adenomas can be missed which increases the risk of patients subsequently developing colorectal cancer. Adenoma detection rate is the most widely used marker of quality, and low rates are associated with increased rates of post-colonoscopy colorectal cancer. Standards of colonoscopy and adenoma detection vary widely between different endoscopists. Interventions to improve adenoma detection rate are therefore required. Many devices have been purported to increase adenoma detection rate. This review looks at current available evidence for device technology to improve adenoma detection rate during colonoscopy.

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Endoscopic tactile instrument for remote tissue palpation in colonoscopic procedures

Bianchi

Trallori

Camboni

et al. 2017

2017 IEEE International Conference on Cyborg and Bionic Systems (CBS)

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Polyp detection rates using magnification with narrow band imaging and white light

Abstract: Our data suggest that the tandem nature of the procedure rather than the optical techniques was associated with the detection of additional polyps' and adenomas.

Cited by 3 publications

References 39 publications

Right-Sided Location Not Associated With Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies

Right-Sided Location Not Associated With Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies

Can technology increase adenoma detection rate?

Endoscopic tactile instrument for remote tissue palpation in colonoscopic procedures

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