Polyparasitism with Malaria and Intestinal Parasite Infections among Infants and Preschool-Aged Children in Egbedore, Osun State, Nigeria

Odoemene, Simon Nnayere; Oluwole, Akinola Stephen; Mogaji, Hammed Oladeji; Adegbola, Mosebolatan Victoria; Omitola, Olaitan Olamide; Bayegun, Adedotun Ayodeji; Ojo, D. A.; Sam-Wobo, S. O.; Ekpo, Uwem Friday

doi:10.1155/2020/8810148

Cited by 5 publications

(5 citation statements)

References 23 publications

(25 reference statements)

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“…Also, there were highly significant differences between the infected and non-infected individuals regarding the GIT symptoms (abdominal pain and diarrhea) ( P < 0.0001). These findings agree with the findings of similar studies 39 . As expected, we observed a significantly higher multiparasitism infection rate among participants with gastrointestinal symptoms compared to the asymptomatic group.…”

Section: Discussionsupporting

confidence: 94%

Mapping gut parasitism patterns in a cohort of Egyptians

El-Wakil

Zalat

El-Badry

2023

Sci Rep

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In developing countries, the prevalence of intestinal parasitic infection is still significant, particularly due to geographical and socioeconomic variables. The objective of this study was to map the distribution pattern of intestinal parasitic infection in a cohort of the Egyptian population, as well as to assess associated risk factors. A cross-sectional hospital-based study was conducted on 386 patients. A single fecal specimen was collected from the study individual and examined microscopically for the detection of parasitic infection. DNA was extracted from all samples and utilized to amplify Entamoeba histolytica complex species, Cryptosporidium species, Giardia intestinalis assemblages, and Blastocystis species using PCRs. Typing of Cryptosporidium species and Giardia intestinalis assemblages was performed using restriction enzymes RasI and HaeIII respectively. While Blastocystis spp. subtypes (ST) were identified through sequencing of PCR products and phylogenetic analysis. 59.6% (230/386) of the study patients were infected with one or more intestinal parasites, 87.4%; 201/230 of patients had mono-parasitic infections, and 12.6%; 29/230 had multiple-parasitic infections (P < 0.0001). The predominant protozoa were Blastocystis, followed by Entamoeba histolytica complex, and Giardia intestinalis both as mono-parasites and as part of multiple parasites. Molecular assays showed that Blastocystis ST3, Entamoeba dispar, Giardia intestinalis assemblage B, and Cryptosporidium hominis were the most prevalent species. Intestinal parasitic infection was significantly associated with age, gender, residence, and water source. Multi-parasitism showed that residency in a rural area was a risk factor (OR 4.49; 95% CI 1.51–13.37; P = 0.007). Egyptians residing in rural areas have a high prevalence of intestinal multi-parasitism. Therefore, to lessen the prevalence and effects of these infections in this group, effective and sustainable control methods, providing health education focusing on good personal hygiene habits, and providing a safe drinking water supply should be implemented.

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Section: Discussionsupporting

confidence: 94%

Mapping gut parasitism patterns in a cohort of Egyptians

El-Wakil

Zalat

El-Badry

2023

Sci Rep

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“…In a recent survey of Nigerian, West African children, a total of 405 children were infected with polyparasitism, 66.17%, 30.12%, and 3.70% for double, triple, and quadruple parasite infections, respectively. Plasmodium falciparum and A. lumbricoides (30.12%); P. falciparum, A. lumbricoides, and T. trichiura (14.81%); and P. falciparum, A. lumbricoides, T. trichiura, and E. histolytica are the most prevalent double, triple, and quadruple parasitic infections recorded [57]. In this West African study, the risk of polyparasitism increased with a child's age.…”

Section: Africa's Infectious Disease Burdenmentioning

confidence: 68%

“…The most common of the STH infections are Ascaris lumbricoides infections, Trichuris trichiura infections, and the hookworm infections caused by Necator americanus and Ancylostoma duodenale, In the less-developed countries of Africa, it is common that children are parasitized with more than one species at the same time over the course of their lifetimes. This protracted hyperparasitemia in young children results in impairments in physical, intellectual, and cognitive development [57]. Significantly, these heavy parasite loads tend to affect the immune response of infected children, which may be directly related to their subsequent responses to SARS-CoV-2 exposures.…”

Section: Africa's Infectious Disease Burdenmentioning

confidence: 99%

“…Many Africans sustain multiple infections simultaneously [53] and this polyparasitism may be dramatically changing the environmental context (and specifically the immunological setting) within which SARS-CoV-2 must adapt. Polyparasitism is widespread in many communities in Sub-Saharan Africa [57] with coinfection of malaria and intestinal helminths is among the most common polyparasitic infections. In a recent survey of Nigerian, West African children, a total of 405 children were infected with polyparasitism, 66.17%, 30.12%, and 3.70% for double, triple, and quadruple parasite infections, respectively.…”

Section: Africa's Infectious Disease Burdenmentioning

confidence: 99%

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Regional Variations And Interrelationships Of Age And Polyparasitism On Covid-19 In Africa

Jackson,

Flowers,

Guthrie

et al. 2023

ACMR

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The patterns of COVID-19 infection in Africa remain something of an enigma. The continent has very high rates of existing parasitemia, particularly in the regions south of the Sahara Desert, has grossly underfunded health care resources, limited access to COVID-19 vaccines, yet appears to have contained the intensity of the COVID-19 pandemic. No specific human genetic adaptations to COVID-19 are expected, given the recency and non-African origins of the specific responsible virus. Broadly distributed existing human genetic polymorphisms may secondarily affect COVID-19 attachment abilities and present the virus with a diverse host environment. The young age of the African population and high levels of existing immunostimulatory polyparasitism, particularly due to intestinal helminths, may stand in the way of explosive continent-wide COVID-19. We propose a coupled model of proximal causes, age and polyparasitism influencing COVID-19 susceptibilities. Regional variation exists within Africa in COVID-19 intensity, suggesting that additional local biocultural factors may be contributing to COVID-19 infection at the local level.

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“…In ethnic, Amara people had significant (AOR 0.39, 95% CI 0.18-0.85) poor practice than otherethnic group. A study in Nigeria, In various community-based parasitic infestation studies, particularly Ara community (14.81%) had the highest cases of intestinal parasites by their poor practice [17]. Mothers who had not able to read and write had four times (AOR 3.97, 95% CI 1.26-12.49) good practice than other educated mothers regarding prevention of intestinal parasitic infections.…”

Section: The Distinction May Be Because Of Instructive Foundation and Financial Variables Between Study Subjects Study Discoveries Of Motmentioning

confidence: 99%

Knowledge and Practice on Prevention of Intestinal Parasitic Infection Among Mothers of Under-five Children in Bulehora Town, Bule Hora, Oromia Region, Southern Ethiopia

Kasimayan

Kasirajan

Rajan

et al. 2021

Preprint

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Background: Intestinal parasitic diseases are one of the general medical conditions in numerous networks, especially among youngsters in country spaces of agricultural nations. Ethiopian studies have concentrated on the commonness and circulation of 2 intestinal parasitic contaminations, fundamentally among younger students. A couple of studies have looked at the scope on knowledge of under-five children’s mothers regarding the prevention of parasitic infections. Methods: A community-based cross-sectional examination with a quantitative methodology was conducted from November 30 to December 30, 2020, among mothers of under-five children in Bule Hora town. The example size in this investigation was 403. The information will be coded, checked sent out to SPSS Statistics rendition 25 for investigation. Result: The general information and practice level concerning mothers of under-five kids in regards to counteraction of intestinal parasitic contaminations was, all among 51.6 % had poor knowledge and 53.1 % had poor practice. Nearly 50% of children not washing of hands and legs after a play in the soil and more than 55% of mothers not advising the child to wear footwear outside the home. Remaining all aspect shows considerably good practice from mother’s mention. In the Ethnic group, Oromo (AOR 2.199, 95% CI 1.05-4.59) people had good knowledge, mothers who not ready to peruse and compose (AOR 0.26, 95% CI 0.12-0.57) had poor knowledge than others. Further in age group (31-35) (AOR 2.94, 95% CI 1.38-6.24) had a good practice, Amara (AOR 0.39, 95% CI 0.18-0.85) people had poor practice and mothers who not able to read and write (AOR 3.97, 95% CI 1.26-12.49) had good practice than other educated.Conclusion: Mothers with children under the age of five have a considerably low degree of optimal awareness and experience when it comes to preventing intestinal parasitic infection. As a result, campaigns or formal training can be used to raise community consciousness about intestinal parasitic invasion counteraction and control.

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Polyparasitism with Malaria and Intestinal Parasite Infections among Infants and Preschool-Aged Children in Egbedore, Osun State, Nigeria

Cited by 5 publications

References 23 publications

Mapping gut parasitism patterns in a cohort of Egyptians

Mapping gut parasitism patterns in a cohort of Egyptians

Regional Variations And Interrelationships Of Age And Polyparasitism On Covid-19 In Africa

Knowledge and Practice on Prevention of Intestinal Parasitic Infection Among Mothers of Under-five Children in Bulehora Town, Bule Hora, Oromia Region, Southern Ethiopia

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