Polypropylene meshes and other alloplastic implants for soft tissue and cartilage nasal reconstructive surgery – a literature review

Ionita, Sabina; Popescu, Şerban Arghir; Lascăr, Ioan

doi:10.1515/rjr-2015-0010

Romanian Journal of Rhinology

2015

DOI: 10.1515/rjr-2015-0010

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Polypropylene meshes and other alloplastic implants for soft tissue and cartilage nasal reconstructive surgery – a literature review

Sabina Ionita

Şerban Arghir Popescu

Ioan Lascăr

Abstract: BACKGROUND. The reconstructive surgery is a domain in continuous research for new techniques and alloplastic materials

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Cited by 3 publications

(1 citation statement)

References 54 publications

(38 reference statements)

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“…In this procedure, three small (18 mm) polyethylene terephthalate rods are inserted in the soft palate mucosal layer sagittally, parallel to each other and spaced 2 mm apart to strengthen them by causing fibrosis and scarring through induction of reaction toward foreign bodies [17,19,20,36]. Research and clinical results have demonstrated that polyethylene terephthalate is a stable, biologically inert compound that is safe for use in humans, as it has been used for decades in other medical devices such as surgical sutures, mesh and vascular grafts [37][38][39][40][41]. In 2004 pillar implants received US FDA clearance to treat snoring and obstructive sleep apnea [42].…”

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confidence: 99%

Efficacy of Pillar Implants to Reduce Snoring and Daytime Sleepiness

et al. 2021

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Objective: To measure the efficacy of pillar implants in reducing snoring. Materials and methods: A total of 30 adult patients who underwent pillar implants were assessed preoperatively and at 1, 3, 6 and 12 months after the implantation. Improvement was measured using snoring frequency, visual analog scale for snoring loudness, and Epworth sleepiness scale for daytime sleepiness. Results: The mean snoring frequency, loudness and Epworth score were reduced from 6.9, 9.2 and 7.4 at the baseline to 5, 5.9 and 5.6, respectively, at 12 months postoperatively (all p < 0.03). The partial implant extrusion rate was 6.7%. Conclusion: We suggest that a pillar implant procedure should be considered before proceeding to more morbid surgeries in patients with snoring and daytime sleepiness.

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Efficacy of Pillar Implants to Reduce Snoring and Daytime Sleepiness

et al. 2021

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Accelerated Discovery of the Polymer Blends for Cartilage Repair through Data-Mining Tools and Machine-Learning Algorithm

2022

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In designing successful cartilage substitutes, the selection of scaffold materials plays a central role, among several other important factors. In an empirical approach, the selection of the most appropriate polymer(s) for cartilage repair is an expensive and time-consuming affair, as traditionally it requires numerous trials. Moreover, it is humanly impossible to go through the huge library of literature available on the potential polymer(s) and to correlate the physical, mechanical, and biological properties that might be suitable for cartilage tissue engineering. Hence, the objective of this study is to implement an inverse design approach to predict the best polymer(s)/blend(s) for cartilage repair by using a machine-learning algorithm (i.e., multinomial logistic regression (MNLR)). Initially, a systematic bibliometric analysis on cartilage repair has been performed by using the bibliometrix package in the R program. Then, the database was created by extracting the mechanical properties of the most frequently used polymers/blends from the PoLyInfo library by using data-mining tools. Then, an MNLR algorithm was run by using the mechanical properties of the polymers, which are similar to the cartilages, as the input and the polymer(s)/blends as the predicted output. The MNLR algorithm used in this study predicts polyethylene/polyethylene-graftpoly(maleic anhydride) blend as the best candidate for cartilage repair.

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Nasal defect reconstruction using cartilage allografts: postoperative complications and cosmetic outcomes

Ivanov,

Khorov,

Yurkovsky

et al. 2024

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This article presents study of immediate and long-term outcomes following 73 nasal reconstruction using cartilage allografts. Postoperative complications developed in 9 cases (12,3%). Two cases (2,7%) were associated with cartilage allograft. Cosmetic outcome was evaluated minimally in 6 months after reconstruction. Patients and experts evaluated 6 particular parameters and total nasal appearance using 5-point scale. Patient scores were higher than expert scores for nasal alar (р=0,001), nostril size (р=0,005), nasal skin color (р=0,028), nasal position (р=0,028). Declined scores were more common registered for parameters nasal alar, nasal dorsum, nostril size, nasal skin color. Experts defined total nasal appearance as acceptable (4 or 5 points) in 62 cases (84,9%). Twelve patients underwent ultrasonography and magnetic resonance tomography of facial tissues in minimally 2 years after reconstruction. Cartilage allografts within reestablished nasal subunits were identified using both methods. No significant deformities and dystrophic changes were discovered. This study showed that allogeneic cadaver cartilage can be used effectively for nasal reconstruction.

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Polypropylene meshes and other alloplastic implants for soft tissue and cartilage nasal reconstructive surgery – a literature review

Abstract: BACKGROUND. The reconstructive surgery is a domain in continuous research for new techniques and alloplastic materials

Cited by 3 publications

References 54 publications

Efficacy of Pillar Implants to Reduce Snoring and Daytime Sleepiness

Efficacy of Pillar Implants to Reduce Snoring and Daytime Sleepiness

Accelerated Discovery of the Polymer Blends for Cartilage Repair through Data-Mining Tools and Machine-Learning Algorithm

Nasal defect reconstruction using cartilage allografts: postoperative complications and cosmetic outcomes

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