Polysaccharide peptides from COV-1 strain of Coriolus versicolor induce hyperalgesia via inflammatory mediator release in the mouse

Chan, Siu‐Lung; Yeung, John H.K.

doi:10.1016/j.lfs.2005.10.011

Cited by 32 publications

(18 citation statements)

References 38 publications

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“…The hot-plate test was used to measure response latencies according to the method described by Chan and Yeung (2006). Animal was placed on the hot plate maintained at 55 ± 0.5°C.…”

Section: Hot-plate Testmentioning

confidence: 99%

Dissection of placebo analgesia in mice: the conditions for activation of opioid and non-opioid systems

Guo

Luo

2009

J Psychopharmacol

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Amanzio and Benedetti (J Neurosci 1999; 19: 484-494) first addressed the conditions necessary for the activation of opioid and non-opioid placebo responses in human. Here, we investigated whether placebo analgesia is subdivided into opioid and non-opioid components in mice by using the model of hot-plate test. Drug conditioning was performed by the combination of the conditioned cue stimulus with the unconditioned drug stimulus, either opioid agonist morphine hydrochloride or non-opioid aspirin. Placebo analgesic responses were evoked by an exposure to a conditioned cue previously paired with drug conditioning. Morphine conditioning produced placebo responses that were completely antagonised by naloxone. By contrast, the conditioned cue after aspirin conditioning elicited a placebo effect that was not blocked by naloxone. Therefore, we first evoked opioid and non-opioid placebo responses in mice that were either naloxone-reversible or naloxone-insensitive, depending on the drug used in conditioning procedure. These findings support that the mechanisms underlying placebo analgesia may depend on the drug conditioning that was originally performed. The present procedure of mice may serve as a model for further understanding of the opioid and non-opioid mechanisms underlying placebo responses.

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“…The hot-plate test was used to measure response latencies according to the method described by Chan and Yeung (2006). Animal was placed on the hot plate maintained at 55 ± 0.5°C.…”

Section: Hot-plate Testmentioning

confidence: 99%

Dissection of placebo analgesia in mice: the conditions for activation of opioid and non-opioid systems

Guo

Luo

2009

J Psychopharmacol

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“…Polysacchride-protein complex, isolated from Coriolus versicolor, has been widely used as an adjunct to cancer chemotherapy and as an immuno-stimulator in china [4]. For example, a protein-bound polysaccharide (PSK), shows beneficial therapeutic effect against various tumors and immunomodulationg activities [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Chemical modification and antitumor activities of two polysaccharide–protein complexes from Pleurotus tuber-regium

Tao

Zhang

2009

International Journal of Biological Macromolecules

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“…Also, studies had shown that the i.p. administration of the polysaccharide extracted (D fraction) from Grifola frondosa (Kodama, Murata, & Nanba, 2004) and of a polysaccharide peptide isolated from Coriolus versicolor mycelia (Chan & Yeung, 2006) enhanced macrophage activation and cytokine production. Furthermore, components or fractions of the Agaricus extract showed an increase in NO production in vitro (Mizuno, & Kawakami, 2006;Mizuno, Kawakami, Sakamoto, & Fujitake, 2003;.…”

Section: Discussionmentioning

confidence: 99%

Agaricus brasiliensismycelium and its polysaccharide modulate the parameters of innate and adaptive immunity

Navegantes

Albuquerque

Dalla-Santa

et al. 2013

Food and Agricultural Immunology

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The biological properties of Agaricus brasiliensis mainly include immunostimulating and antitumour activities. This study evaluated the immunomodulating effect of A. brasiliensis mycelium (LPB) and its exopolysaccharides (EPS) on immunological parameters, such as phagocytosis of Candida albicans and nitric oxide (NO) production by infected macrophages, splenocytes proliferation in response to C. albicans. It also assessed the effects of the intake of LPB on the number of lymphocytes in the lymph node and spleen of treated animals and the TNF-a production. It was showed that the LPB and EPS had opposite effects; LPB had antiproliferative action and also reduced the NO levels produced by macrophages. However, the EPS showed an immune-stimulating effect potentiating the splenocytes proliferation and NO production from macrophages after stimulation with C. albicans. In addition, it also protected the macrophages from death induced by yeast. These data confirmed the immunomodulatory properties of LPB and its polysaccharides.

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Polysaccharide peptides from COV-1 strain of Coriolus versicolor induce hyperalgesia via inflammatory mediator release in the mouse

Cited by 32 publications

References 38 publications

Dissection of placebo analgesia in mice: the conditions for activation of opioid and non-opioid systems

Dissection of placebo analgesia in mice: the conditions for activation of opioid and non-opioid systems

Chemical modification and antitumor activities of two polysaccharide–protein complexes from Pleurotus tuber-regium

Agaricus brasiliensismycelium and its polysaccharide modulate the parameters of innate and adaptive immunity

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