Polystyrene Pocket Lithography: Sculpting Plastic with Light (Adv. Mater. 27/2022)

Samal, Pinak; Sámal, J; Gubbins, Eva; Vroemen, Pascal; Blitterswijk, Clemens van; Truckenmüller, Roman; Giselbrecht, Stefan

doi:10.1002/adma.202270201

Cited by 5 publications

(6 citation statements)

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“…[ 46 ] This alignment is essential for maintaining normal vascular function [ 46 ] and surface topographies have been extensively studied to induce such orientation. [ 47–49 ] Electrospun fibers, in particular, have emerged as one of the most popular scaffolds for investigating cell alignment due to their tunable fiber diameter and orientation. [ 3,50,51 ] In our study, we aimed to investigate the capability of our replicated fiber imprints to influence cell orientation by culturing HUVECs on our random fiber imprint b and aligned fiber imprint d ( Figure A).…”

Section: Resultsmentioning

confidence: 99%

The Synergy of Electrospinning and Imprinting for Faithful Replication of Fiber Structures

Şahin

Vrij

Grant

et al. 2023

Adv Materials Technologies

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Electrospinning is a powerful method to fabricate structures resembling the fibrous texture of the native extracellular matrix. However, the random fiber deposition of the process hinders a faithful reproduction of the fiber mesh morphology on multiple samples, which raises difficulties in experimental designs to systematically test and assess cell response in vitro. A multi‐replication process to precisely reproduce the fiber morphology on different cell culture substrates is developed. The process involves a decoupling of the fiber structure, material, and porosity by combining the key advantages of electrospinning and imprinting. With this, fiber patterns having a diameter between 0.4 and 2.8 µm are replicated on polycarbonate, polystyrene, poly(methyl methacrylate), and cyclic olefin copolymer films. Identical fiber morphology is, then, obtained on porous films having a pore diameter between 2 and 12 µm. Having full control over these parameters allows the multireplication process to engineer well‐characterized cell microenvironments, which can potentially be used to further investigate complex cell–material interactions.

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Section: Resultsmentioning

confidence: 99%

The Synergy of Electrospinning and Imprinting for Faithful Replication of Fiber Structures

Şahin

Vrij

Grant

et al. 2023

Adv Materials Technologies

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“…[ 200 ] Finally, innovative strategies for engineering artificial cells with diverse morphologies (e.g., multicompartment and surficial microstructure) should be explored in order to accurately imitate different types of actual cells (e.g., neurons, dendritic cells, and fertilized egg cells). [ 201 ]…”

Section: Conclusion and Prospectmentioning

confidence: 99%

Recent Advances in Microfluidic Technologies for the Construction of Artificial Cells

Tan

Yin

et al. 2023

Adv Funct Materials

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Artificial cells are synthetic constructs that emulate natural cells, with potential applications in areas of energy science, environmental treatment, and the study of life's origins. Nevertheless, the construction of artificial cells is a formidable undertaking, given the intricate nature of natural cells in structures, functions, and working mechanisms. With precise control, high automation, and excellent uniformity, microfluidics has emerged as a promising approach for the construction of artificial cells. This review summarizes the latest microfluidic techniques utilized to construct artificial cells, ranging from simple droplets to sophisticated cell‐inspired systems. These include the generation of droplets, the production of vesicles (lipid‐based and polymer‐based vesicles), the fabrication of polymeric microparticles with various compartments, shapes, and microstructures, as well as the manufacture of sophisticated cell‐inspired systems. The characteristics of different methods for the construction of artificial cells are discussed in detail. Furthermore, the wide‐ranging applications of artificial cells are also showcased. Finally, contemporary obstacles and forthcoming advancements are discussed in the field of microfluidic‐based artificial cells. This review is supposed to stimulate research in the construction of more functional and natural‐like artificial cells, as well as works in the fields of material, biology, environment, medicine, and energy.

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“…Spreading tiny microdroplets is one of the most critical applications of microfluidics. [ 2,6,11,145,146 ] Homogeneous and highly dispersed droplets can be rapidly generated and manipulated using immiscible multiphase flows inside microchannels. After nearly twenty years of development, this field has matured.…”

Section: Emerging Applicationsmentioning

confidence: 99%

“…Driven by the desire for miniaturization and planarization of biochemistry devices for analysis, detection, and separation, microfluidic technology has experienced explosive development in the past few decades. [ 1–8 ] The rise and vigorous growth of microfluidic technology enable the precise control and operation of microliter or less liquid. Microfluidics‐based lab‐on‐a‐chip and micrototal analysis systems (µTAS) have therefore been established.…”

Section: Introductionmentioning

confidence: 99%

Bioinspired Superwetting Open Microfluidics: From Concepts, Phenomena to Applications

et al. 2023

Adv Funct Materials

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Microfluidics and bioinspired superwetting materials, as two crucial branches of scientific research, are entering their golden age of development. As an emerging interdisciplinary subject of these two fields, bioinspired superwetting open microfluidics is triggering technological revolutions in many disciplines, including rapid medical diagnosis, biochemical analysis, liquid manipulation, 3D printing, etc. However, this new research area has yet to attract extensive attention. So, a timely review is necessary to organize the development process, summarize current achievements, and discuss the challenges or chances for the ongoing scientific trend. In this review, the evolution from closed to open microfluidics is combed first. Then, three typical bioinspired superwetting systems are introduced emphatically. Based on this, the bioinspired superwetting open microfluidics is divided into different categories according to the bionic objects as the focus of this study. Taking natural phenomena as the entry point, the research from the underlying mechanism to the application is systematically discussed and summarized. Several emerging applications are also mentioned. Finally, some views on major problems, existing challenges, and developing trends are briefly put forward in this field to guide future research.

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Polystyrene Pocket Lithography: Sculpting Plastic with Light (Adv. Mater. 27/2022)

Cited by 5 publications

References 0 publications

The Synergy of Electrospinning and Imprinting for Faithful Replication of Fiber Structures

The Synergy of Electrospinning and Imprinting for Faithful Replication of Fiber Structures

Recent Advances in Microfluidic Technologies for the Construction of Artificial Cells

Bioinspired Superwetting Open Microfluidics: From Concepts, Phenomena to Applications

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