Polythiophene nanofilms for sensitive fluorescence detection of viruses in drinking water

Abstract

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Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection

“…This sensing platform used electrochemiluminescence as a detection system by utilizing EuS nanocrystals attached to polyacrylic acid, achieving a working range of 3 fM to 0.3 nM with an LOD of 0.3 fM. Wankar et al [182] produced an eMIP based platform for the detection of tobacco necrosis virus (TNV) using 200 nm nanofilms of polythiophene. The ~20 nm imprints in the polymer film were verified via Atomic Force Microscopy (AFM).…”

Nanomaterials for virus sensing and tracking

“…414 Organic nanomaterials can themselves be harnessed as receptors 124 or transducers 415 and are the nanomaterial of choice in optical virus sensors. 11,319,414,416,417 They possess intrinsic bioinertness as well as biocompatibility. Nanomaterials such as MIP nanoparticles (MIP-NPs) offer cost-effective alternatives to the delicate antibodies often used in virus detection.…”

“…76 Polythiophene MIP-NPs (200 nm) emit fluorescence (l: 410 nm) and their thickness can be optimized to obtain a response within 2 minutes. 417 This year, a Pb 2+ ion-imprinted terpyridine-based polymer was developed as a transducer in the genosensing of the HIV-1 polgene. 415 4.1.4 Other organic nanomaterials.…”

Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

“…Electropolymerization is another elegant and widely applied technique for the preparation of MIP-based biomimetic sensors for both low-molecular-weight analytes and biomacromolecules and, to some extent, for viruses, as it allows the preparation of MIPs directly on a transducer’s surface under mild conditions [ 19 , 20 , 46 , 62 , 106 , 108 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 ]. The thickness of the polymeric film can be easily adjusted by just simply controlling the charge passed through, which results in more effective template removal and rebinding processes.…”