Poor glucose regulation is associated with declines in well-being among older men, but not women.

Mantantzis, Konstantinos; Drewelies, Johanna; Duezel, Sandra; Buchmann, Nikolaus; Steinhagen‐Thiessen, Elisabeth; Wagner, Gert G.; Raz, Naftali; Lindenberger, Ulman; Demuth, Ilja; Gerstorf, Denis

doi:10.1037/pag0000404

Cited by 3 publications

(2 citation statements)

References 57 publications

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“…Direct effects were analyzed using multiple regression with discrimination, depression, and anxiety entered as predictors; well-being entered as the outcome; and gender, income, perceived health, smoking status, age, exercise, and insulin resistance entered as covariates. All covariates were selected based on sample size constraints and potential to act as confounds, as previous studies have reported associations between these factors and both discrimination [10,11,31,32] and well-being [33][34][35][36][37][38]. Glycemic control (i.e., HbA1c) was initially considered as a covariate in place of insulin resistance, but the latter was chosen for the final model because it shared a significant correlation with at least one other variable in the model, and is considered a more reliable indicator of longterm metabolic health [39].…”

Section: Discussionmentioning

confidence: 99%

Depression and Anxiety Mediate the Relationship between Discrimination and Well-Being in a Sample of Latinx Adults with Type 2 Diabetes: Results from a Dual Mediation Analysis

Matlock,

Pérez-Escamilla,

Wagner

2024

J Immigrant Minority Health

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Latinxs experience greater risk for type 2 diabetes, discrimination, and poor mental health. The pathways linking these factors, however, are not well understood. This study tested whether depression and anxiety mediated the relationship between discrimination and well-being. Bootstrapped mediation tests were conducted using a sample of Latinx adults with type 2 diabetes (n = 121) and regression models adjusted for demographic and health covariates. Depression and anxiety fully and jointly mediated the effect of discrimination on well-being; everyday discrimination was linked to elevated symptoms of depression and anxiety which were, in turn, independently linked to reduced emotional well-being. Moreover, the effect size for the anxiety pathway (β=–0.13) was 60% larger than for depression (β=–0.08). Dual mediation suggests depression, and especially anxiety, may be important targets for interventions seeking to mitigate the deleterious effects of discrimination. Findings have important implications for psychotherapeutic treatments and public health policy.

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Section: Discussionmentioning

confidence: 99%

Depression and Anxiety Mediate the Relationship between Discrimination and Well-Being in a Sample of Latinx Adults with Type 2 Diabetes: Results from a Dual Mediation Analysis

Matlock,

Pérez-Escamilla,

Wagner

2024

J Immigrant Minority Health

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“…This is even more dramatic since almost one third of the participants was not aware of the disease (Table 1). In addition being a risk factor for cardiovascular disease and cognitive decline, a recent analysis of BASE-II data suggested that the capacity to regulate the glucose metabolism is associated with well-being among older men 43 .…”

Section: What Has Been Found?mentioning

confidence: 99%

Cohort Profile Update: GendAge and Berlin Aging Study II (BASE-II)

Demuth

Banszerus

Drewelies

et al. 2020

Preprint

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The study Sex- and gender-sensitive prevention of cardiovascular and metabolic disease in older adults in Germany, the GendAge study, focusses on major risk factors for cardiovascular and metabolic diseases and on the development of major outcomes from intermediate phenotypes in the context of biological sex and gender differences. It is based on a re-investigation of participants of the Berlin Aging Study II (BASE-II). The Berlin Aging Study II (BASE-II) is aiming at identifying factors that distinguish healthy from unhealthy ageing and completed baseline assessments in 2,200 adult volunteers (1,600 participants aged 60-80 years and 600 participants aged 20-35 years) in 2014. The BASE-II follow-up assessments of 1,100 men and women aged 65-94 years in 2018-2020 were part of GendAge. In addition to re-assessing most baseline measures (geriatrics, internal medicine, immunology and psychology) we implemented a comprehensive gender questionnaire covering socio-cultural gender characteristics and added high-quality echocardiography.

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Physical activity participation among older adults with diabetes: Applying the World Health Organization’s International Classification of Functioning, Disability and Health (ICF) Guidelines

Yang

Mpofu

et al. 2021

The Australian Journal of Rehabilitation Counselling

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Objective: Physical activity (PA) is a known benefit to older adults with diabetes; however, the determinants of PA are less well studied in this population. Applying the World Health Organization’s International Classification of Functioning, Disability and Health (ICF), a well-established biopsychosocial framework, we explored PA participation among older adult with type 2 diabetes. Method: Using data from the Health and Retirement Study and the RAND Center for the Study of Aging (N = 2,016; mean age = 73.19; SD = 6.16), we conducted hierarchical stepwise regression analysis to evaluate the relative contribution of different biopsychosocial predictors to PA – namely, body functions and structure, activity and participation, personal, and environmental factors. Results: Altogether, biopsychosocial factors accounted for 20% of the variance in PA participation. Of the personal factors, high extraversion and low neuroticism explained approximately 54% of the variance in PA among the older adults – beyond sociodemographics. Low body mass index, reduced pain, reduced depression, and higher cognitive functioning also had good explanatory power (25% of explained variance), whereas activity participation and environment did not (10% each). Conclusion: Aligning care with components of the ICF will help to ensure a focus on person-centric practices and, in turn, optimize participation outcomes such as PA.

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Poor glucose regulation is associated with declines in well-being among older men, but not women.

Cited by 3 publications

References 57 publications

Depression and Anxiety Mediate the Relationship between Discrimination and Well-Being in a Sample of Latinx Adults with Type 2 Diabetes: Results from a Dual Mediation Analysis

Depression and Anxiety Mediate the Relationship between Discrimination and Well-Being in a Sample of Latinx Adults with Type 2 Diabetes: Results from a Dual Mediation Analysis

Cohort Profile Update: GendAge and Berlin Aging Study II (BASE-II)

Physical activity participation among older adults with diabetes: Applying the World Health Organization’s International Classification of Functioning, Disability and Health (ICF) Guidelines

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