‘Poppers maculopathy’—an emerging ophthalmic reaction to recreational substance abuse

Poppers: legal highs with questionable contents? A case series of poppers maculopathy

“…This supports previous findings; a patient with a 12-year history of poppers use demonstrated complete restitution on OCT 6 months after cessation 18. One of the few exceptions to this was a case who had used poppers regularly for years and who showed no improvement at 3 months, objective or subjective, following cessation 12. It would be interesting to know the outcome after a longer period of follow-up.…”

Adverse ophthalmic reaction in poppers users: case series of ‘poppers maculopathy’

“…Case 1 in this series has recently been published. 13 Given the longstanding use of poppers, 1 the question arises as to why maculopathy associated with poppers use has not been recognised until 2010. 7 Up to 2007, isobutyl nitrite was the most commonly used compound in poppers in the United Kingdom.…”

Poppers toxic maculopathy misdiagnosed as atypical optic neuritis

“…In France, up to 14% of young people under age 18 and 10% of the UK general population reported having already tried poppers [1]. A few cases of retinal toxicity have been reported [1][2][3][4][5][6].…”