Pore structure of cadmium oxide

Mikhail, R. Sh.; Kamel, A. M.

doi:10.1021/j100727a018

Cited by 10 publications

(4 citation statements)

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“…The BJH pore size distribution of Sample 3 [Figure 6 b(2)] shows that its mesopores are in the size range of 1.3–4.0 nm and that the peak was centered at around 2.5 nm. These luminescent particles thus have a typical porous structure 31–33. The porous structure of the particles depends strongly on the thickness of the SiO 2 shell.…”

Section: Resultsmentioning

confidence: 99%

Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

et al. 2015

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Selective inhibitors of the protein tyrosine phosphatase SHP2 (src homology region 2 domain phosphatase; PTPN11), an enzyme that is deregulated in numerous human tumors, were generated through a combination of chemical synthesis and structure-based rational design. Seventy pyridazolon-4-ylidenehydrazinyl benzenesulfonates were prepared and evaluated in enzyme assays. The binding modes of active inhibitors were simulated in silico using a newly generated crystal structure of SHP2. The most powerful compound, GS-493 (4-{(2Z)-2-[1,3-bis(4-nitrophenyl)-5-oxo-1,5-dihydro-4H-pyrazol-4-yliden]hydrazino}benzenesulfonic acid; 25) inhibited SHP2 with an IC50 value of 71±15 nM in the enzyme assay and was 29- and 45-fold more active toward SHP2 than against related SHP1 and PTP1B. In cell culture experiments compound 25 was found to block hepatocyte growth factor (HGF)-stimulated epithelial-mesenchymal transition of human pancreatic adenocarcinoma (HPAF) cells, as indicated by a decrease in the minimum neighbor distances of cells. Moreover, 25 inhibited cell colony formation in the non-small-cell lung cancer cell line LXFA 526L in soft agar. Finally, 25 was observed to inhibit tumor growth in a murine xenograft model. Therefore, the novel specific compound 25 strengthens the hypothesis that SHP2 is a relevant protein target for the inhibition of mobility and invasiveness of cancer cells.

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Section: Resultsmentioning

confidence: 99%

Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

et al. 2015

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“…A Barrett-Joyner-Halenda (BJH) analysis showed that their mesoporosities are 0.16 and 0.22 cm 3 g, respectively. The T-plot [31,32] for Sample 1 [ Figure 6 a (2)] indicates that the pore size is 1.2 nm. The morphology of the mesopores was further found to be of type IV, for which the N 2 adsorption-desorption isotherm shows pronounced hysteresis during reverse scan [ Figure 6 b(1)].…”

Section: Porous Structure Of Luminescent Sio 2 Particlesmentioning

confidence: 99%

“…These luminescent particles thus have a typical porous structure. [31][32][33] The porous structure of the particles depends strongly on the thickness of the SiO 2 shell.…”

Section: Porous Structure Of Luminescent Sio 2 Particlesmentioning

confidence: 99%

Size‐Tunable Highly Luminescent SiO₂ Particles Impregnated with Number‐Adjusted CdTe Nanocrystals

Yang

Murase

2010

ChemPhysChem

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Highly luminescent SiO(2) particles impregnated with CdTe nanocrystals (NCs) are prepared by a sol-gel procedure. Partial ligand exchange from thioglycolic acid to 3-mercaptopropyltrimethoxysilane (MPS) on the NCs enables retention of the initial photoluminescence (PL) efficiency of the NCs in water, while the simultaneous addition of a poor solvent (ethanol) results in regulated assembly of the NCs through condensation of hydrolyzed MPS. The SiO(2) particles thus prepared have, for example, a diameter of 16 nm and contain three NCs each. The PL efficiency of these particles is 40 %, while the initial efficiency is 46 % in a colloidal solution. The redshift and narrowed spectral width in PL observed after impregnation indicate that the concentration of NCs in these nearly reaches the ultimate value (on the order of 10(21) particles per liter). The porosity of these particles is investigated by means of N(2) adsorption-desorption isotherms. Due to the SiO(2) shell, these particles have higher stability in phosphate-buffered saline buffer solution than the initial NCs. Their potential use for labeling in bio-applications is investigated by conjugating biotinylated immunoglobulin G to them by using streptavidin maleimide as linker. Successful conjugation is confirmed by electrophoresis in agarose gel. This preparation method is an important step towards fabricating intensely emitting biocompatible SiO(2) particles impregnated with semiconductor NCs.

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“…The carrier concentration of CdO, which can be strongly affected by the processing conditions, is reported to be varying from 10 18 to 10 20 cm −3 in literatures . Table lists the room‐temperature carrier concentration n and mobility μ of the present CdO samples.…”

Section: Resultsmentioning

confidence: 97%

Enhanced high‐temperature thermoelectric performance of CdO ceramics with randomly distributed micropores

Liu

Gao

et al. 2017

J Am Ceram Soc

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CdO ceramics with randomly distributed micropores were synthesized by the conventional solid-state reaction method via adding polymethyl methacrylate (PMMA) as the void forming agent. The introduction of microsized pores can significantly affect both electrical and thermal transport properties of the CdO matrix, and possible underlying mechanisms are discussed. Due to the dramatically reduced thermal conductivity, a highest ZT value of~0.51 has been achieved in the porous CdO at about 1000 K, increased by about 52% as compared to that of the dense sample without PMMA addition. This work demonstrates that introducing microsized pores is a very simple, low-cost, and efficient strategy to improve the high-temperature thermoelectric performance of CdO ceramics. K E Y W O R D S

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Pore structure of cadmium oxide

Cited by 10 publications

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Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

Size‐Tunable Highly Luminescent SiO₂ Particles Impregnated with Number‐Adjusted CdTe Nanocrystals

Enhanced high‐temperature thermoelectric performance of CdO ceramics with randomly distributed micropores

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Pore structure of cadmium oxide

Cited by 10 publications

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Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

Size‐Tunable Highly Luminescent SiO2 Particles Impregnated with Number‐Adjusted CdTe Nanocrystals

Enhanced high‐temperature thermoelectric performance of CdO ceramics with randomly distributed micropores

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Size‐Tunable Highly Luminescent SiO₂ Particles Impregnated with Number‐Adjusted CdTe Nanocrystals