Porous Coatings in Orthopedics

Kohn, David H.

doi:10.1016/b978-0-08-055294-1.00201-4

Cited by 6 publications

(6 citation statements)

References 179 publications

(182 reference statements)

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“…As described earlier, these metal combinations (though in different proportions) are present in stents, prosthodontic and orthopaedic implants, such as ASTM F90 (Co-20Cr-15W-10Ni) [93][94][95][96]. No such carcinogenicity has been reported for these applications.…”

Section: Toxicity Of Tungstenmentioning

confidence: 99%

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The use of tungsten as a chronically implanted material

Idil

Donaldson

2018

J. Neural Eng.

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This review paper shows that tungsten should not generally be used as a chronically implanted material. The metal has a long implant history, from neuroscience, vascular medicine, radiography, orthopaedics, prosthodontics, and various other fields, primarily as a result of its high density, radiopacity, tensile strength, and yield point. However, a crucial material criterion for chronically implanted metals is their long-term resistance to corrosion in body fluids, either by inherently noble metallic surfaces, or by protective passivation layers of metal oxide. The latter is often assumed for elemental tungsten, with references to its 'inertness' and 'stability' common in the literature. This review argues that in the body, metallic tungsten fails this criterion, and will eventually dissolve into the soluble hexavalent form W, typically represented by the orthotungstate [Formula: see text] (monomeric tungstate) anion. This paper outlines the metal's unfavourable corrosion thermodynamics in the human physiological environment, the chemical pathways to either metallic or metal oxide dissolution, the rate-limiting steps, and the corrosion-accelerating effects of reactive oxidising species that the immune system produces post-implantation. Multiple examples of implant corrosion have been reported, with failure by dissolution to varying extents up to total loss, with associated emission of tungstate ions and elevated blood serum levels measured. The possible toxicity of these corrosion products has also been explored. As the field of medical implants grows and designers explore novel solutions to medical implant problems, the authors recommend the use of alternative materials.

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Section: Toxicity Of Tungstenmentioning

confidence: 99%

“…In orthopaedics, cobalt-based wrought alloy ASTM F90 is used for total joint replacement; its composition is Co-20Cr-15W-10Ni. W composition is 14-16% (wt%) [95]. It is a popular orthopaedic alloy [96].…”

Section: W Alloys In Medical Implantsmentioning

confidence: 99%

The use of tungsten as a chronically implanted material

Idil

Donaldson

2018

J. Neural Eng.

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“…Copper and titanium, as separate components, are well-known and used as biomaterials [1][2][3][4]. The properties of Cu-Ti composites have been examined from the mid-twentieth century, and since then, their interactions with microorganisms and the tissues of higher organisms have been investigated extensively.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Nanocrystalline Cu–Ti Thin Films Enhance Survival and Induce Proliferation of Mouse Fibroblasts In Vitro

et al. 2021

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This paper describes the effect of a nanocrystalline thin film based on copper and titanium on mouse fibroblast cells. Cu–Ti coatings were prepared using magnetron sputtering. In their composition was 25 at.% Cu and 75 at.% Ti. The goal of the study was to evaluate the effect of the material on the survival, migration, and proliferative capabilities of mouse L929 fibroblasts. The Cu25Ti75 material had no effect on the induction of cell death and did not disturb the cell cycle phase. The study showed a unique effect of a Cu25Ti75 thin film on mouse fibroblast cells, and the results concerning mitochondrial activity, cell proliferation, and migration proved that the material is nontoxic and shows proliferative properties in a wound healing test. The possible biomedical applications of the new nanocrystalline thin film biomaterial with multifunctional properties are described.

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“…For certain applications, however, such coatings are too thin and porous [1]. There is an increasing number of experimental and numerical studies aimed at investigating the shape, microstructure and spatial distribution of pores and at analyzing methods for estimating the porosity and producing porous coatings (see, e.g., [2]).…”

Section: Introductionmentioning

confidence: 99%

A numerical simulation of the deformation and fracture of a material with a porous polysilazane coating

Балохонов¹,

Zinoviev²,

Романова³

et al. 2014

AIP Conference Proceedings

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A numerical analysis of the deformation and fracture mechanisms involved in a material with a porous ceramic coating under tension and compression is presented. The dynamic boundary-value problem in the plane strain formulation is solved numerically by the finite difference method. To take an explicit account of the substrate-coating interface and porous coating microstructure in the calculations, a curvilinear mesh generation algorithm based on the solution according to elasticity theory has been developed. A two-dimensional curvilinear mesh generated in this work was used to simulate the uniaxial loading of a material with a porous coating. The fundamental difference between the fracture mechanisms operating in the coated material in the cases of tension and compression was found to be related with the formation of local regions experiencing bulk tension in both cases

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Porous Coatings in Orthopedics

Cited by 6 publications

References 179 publications

The use of tungsten as a chronically implanted material

The use of tungsten as a chronically implanted material

Multifunctional Nanocrystalline Cu–Ti Thin Films Enhance Survival and Induce Proliferation of Mouse Fibroblasts In Vitro

A numerical simulation of the deformation and fracture of a material with a porous polysilazane coating

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