Porous crosslinked PDMS-microchannels coatings

Juchniewicz, Marcin; Stadnik, Dorota; Biesiada, K.; Olszyna, A.; Chudy, M.; Brzózka, Zbigniew; Dybko, Artur

doi:10.1016/j.snb.2006.10.041

Cited by 30 publications

(23 citation statements)

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“…For example, they have been used as membranes for separation and purification (Gu & Miki 2007), solid supports for biosensor, biomedicine and catalysts (Janshoff et al 1998;Grayson et al 2003;Buriak 2006), scaffolds for tissue regeneration (Rezwan et al 2006), and so forth. A porous polydimethylsiloxane (PDMS) structure was used in microfluidic systems as a microfilter (Kobayashi et al 1993) and porous microchannels for gas sensor (Juchniewicz et al 2007). These porous PDMS structures were fabricated based on templating using self-assembled colloidal microspheres (Li & Zhang 2007), emulsion polymerization (Dufaud et al 2002), and surface treatment using a CO 2 -pulsed laser (Khorasani et al 2005) and phase separation (Khorasani et al 2005).…”

Section: Introductionmentioning

confidence: 99%

A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge

Kim

2011

Biomed Microdevices

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In this paper, we propose a novel portable and disposable pressure pump using a porous polydimethylsiloxane (PDMS) sponge and demonstrate its application to a microfluidic lab-on-a-chip. The porous PDMS sponge was simply fabricated by a sugar leaching technique based on capillary suction of pre-cured PDMS into lumps of sugar, thereby enabling us to achieve the porous PDMS sponge composed of interconnected micropores. To indicate the characteristics of the porous PDMS sponge and pump, we measured the average porosities of them whose values were 0.64 and 0.34, respectively. A stress-strain relationship of the fabricated portable pressure pump represented a linear behavior in the compressive strain range of 0 to 20%. Within this range, a pumping volume of the pressure pump could be linearly controlled by the compressed strain. Finally, the fabricated porous PDMS pump was successfully demonstrated as a portable pressure pump for a disposable microfluidic lab-on-a-chip for efficient detection of agglutination. The proposed portable pressure pump can be potentially applicable to various disposable microfluidic lab-on-a-chip systems.

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Section: Introductionmentioning

confidence: 99%

A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge

Kim

2011

Biomed Microdevices

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“…Oxygen Permeable Membrane Fabrication. Thin semipermeable nanoporous membrane (Figure 2(b)) was prepared by changing an already communicated protocol [31]. Briefly, a mixture of PDMS-curing agent (10 : 1 w/w) and deionized ultrapure water, used as a porogen agent at a ratio of 50%, was stirred for 30 min and degassed to remove any residual air bubbles.…”

Section: Apparatus and Procedures Microfabrication Processesmentioning

confidence: 99%

Microoxygraph Device for Biosensoristic Applications

et al. 2016

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Oxygen consumption rate (OCR) is a significant parameter helpful to determinein vitrorespiratory efficiency of living cells. Oxygen is an excellent oxidant and its electrocatalytic reduction on a noble metal allows accurately detecting it. By means of microfabrication technologies, handy, low-cost, and disposable chip can be attained, minimizing working volumes and improving sensitivity and response time. In this respect, here is presented a microoxygraph device (MOD), based on Clark’s electrode principle, displaying many advantageous features in comparison to other systems. This lab-on-chip platform is composed of a three-microelectrode detector equipped with a microgrooved electrochemical cell, sealed with a polymeric reaction chamber. Au working/counter electrodes and Ag/AgCl reference electrode were fabricated on a glass slide. A microchannel was realized by photoresist lift-off technique and a polydimethylsiloxane (PDMS) nanoporous film was integrated as oxygen permeable membrane (OPM) between the probe and the microreaction chamber. Electrochemical measurements showed good reproducibility and average response time, assessed by periodic injection and suction of a reducing agent. OCR measurements on 3T3 cells, subjected, in real time, to chemical stress on the respiratory chain, were able to show that this chip allows performing consistent metabolic analysis.

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“…A common process for generating porous structures involves a pore generator, called porogen. These porous PDMS materials can be prepared using sugar, salt, self‐assembled colloidal microspheres, suspension polymerization, emulsion droplets, and CO 2 gas generated by NaHCO 3 as templates, among which the sacrificial sugar template technique has been the most popular because of its simple steps, cost effectiveness, and ecofriendliness . Recently, porous PDMS materials have been successfully synthesized for selective oil absorption from water.…”

Section: Introductionmentioning

confidence: 99%

Preparation and morphology control of three‐dimensional interconnected microporous PDMS for oil sorption

Wang

Zhao

et al. 2015

Polymers for Advanced Techs

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This study described an approach to impart controlled morphology and improved pore interconnectivity to poly(dimethylsiloxane) (PDMS) sponges for oil sorption by partially fusing the sugar particles together prior to creation of a continuous PDMS matrix. PDMS sponges with high absorption capacity, low water pickup, and remarkable reusability were fabricated by the polymerization of the PDMS prepolymer and a curing agent in cyclohexane. The PDMS sponge showed oil absorbency in the range from 790% to 4000% for various oils solvents, with the maximum absorption capacity reaching up to 23 times of its weight. Compressive modulus of PDMS subjected to sugar fusion for 24 hr was significantly increased to 1900 Mpa. The sponge also exhibited excellent repellency to corrosive strong acid and alkali. Besides, oil can be quickly adsorbed in tens of seconds and maintained for several months. Furthermore, PDMS sponges showed little loss of their absorption capacities and owned weights after 20 absorbing/recovering cycles. Copyright © 2015 John Wiley & Sons, Ltd.

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Porous crosslinked PDMS-microchannels coatings

Cited by 30 publications

References 0 publications

A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge

A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge

Microoxygraph Device for Biosensoristic Applications

Preparation and morphology control of three‐dimensional interconnected microporous PDMS for oil sorption

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