Porous graphene oxide/chitosan beads with honeycomb-biomimetic microchannels as hydrophilic adsorbent for the selective capture of glycopeptides

Li, Kun; Zhao, B; Yu, Qingcai; Xu, Juan; Li, Xuewei; Wei, Diandian; Qian, Lisheng; Liu, Guodong; Wang, Wenrui

doi:10.1007/s00604-020-04266-y

Cited by 20 publications

(8 citation statements)

References 35 publications

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Section: Chitosan/graphene Compositesmentioning

confidence: 99%

“…Indeed, it has been shown by Fan et al [155] using FTIR measurements, that the -NH groups on the chitosan chains react with the -COOH groups of GO to form a linking -NHCO-group. Using these approaches, CS/GO composites have been formed as beads [156], membranes [157,158] and columns [144,159] and employed successfully as adsorbents for the removal of pollutants from aqueous media. Several studies have been reported using CS/GO composites and these hydrogels have been employed to adsorb and remove various dyes from water [160], heavy metal ions [161], phenolic compounds [162] and pharmaceutical and personal care products [163].…”

Section: Chitosan/graphene Compositesmentioning

confidence: 99%

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Recent Developments in Chitosan-Based Adsorbents for the Removal of Pollutants from Aqueous Environments

et al. 2021

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The quality of water is continuously under threat as increasing concentrations of pollutants escape into the aquatic environment. However, these issues can be alleviated by adsorbing pollutants onto adsorbents. Chitosan and its composites are attracting considerable interest as environmentally acceptable adsorbents and have the potential to remove many of these contaminants. In this review the development of chitosan-based adsorbents is described and discussed. Following a short introduction to the extraction of chitin from seafood wastes, followed by its conversion to chitosan, the properties of chitosan are described. Then, the emerging chitosan/carbon-based materials, including magnetic chitosan and chitosan combined with graphene oxide, carbon nanotubes, biochar, and activated carbon and also chitosan-silica composites are introduced. The applications of these materials in the removal of various heavy metal ions, including Cr(VI), Pb(II), Cd(II), Cu(II), and different cationic and anionic dyes, phenol and other organic molecules, such as antibiotics, are reviewed, compared and discussed. Adsorption isotherms and adsorption kinetics are then highlighted and followed by details on the mechanisms of adsorption and the role of the chitosan and the carbon or silica supports. Based on the reviewed papers, it is clear, that while some challenges remain, chitosan-based materials are emerging as promising adsorbents.

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Section: Chitosan/graphene Compositesmentioning

confidence: 99%

Section: Chitosan/graphene Compositesmentioning

confidence: 99%

Recent Developments in Chitosan-Based Adsorbents for the Removal of Pollutants from Aqueous Environments

et al. 2021

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“…Non‐destructive and specific enrichment of N‐glycopeptides is achieved by the hydrophilic interaction between branched N‐glycans and materials. In order to discover potential HILIC materials for more efficient enrichment of glycopeptides, various modified HILIC materials have been employed, including zwitterionic‐based hydrophilic materials [40], carbohydrate‐based hydrophilic materials [41], polymer‐based hydrophilic materials [42], organic frameworks‐based materials [43]. Different kinds of polar groups, including zwitterions, sulfonic acids, amides, and diols, have been modified onto various substrates, such as graphene oxide (GO) [44], silica [45], magnetic nanoparticles [46].…”

Section: Sample Preparation and Enrichment For Protein Glycosylation ...mentioning

confidence: 99%

Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

et al. 2022

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As the common and significant chemical modifications, post‐translational modifications (PTMs) play a key role in the functional proteome. Affected by the signal interference, low concentration, and insufficient ionization efficiency of impurities, the direct detection of PTMs by mass spectrometry (MS) still faces many challenges. Therefore, sample preparation and enrichment are an indispensable link before MS analysis of PTMs in proteomics. The rapid development of functionalized materials with diverse morphologies and compositions provides an avenue for sample preparation and enrichment for PTMs analysis. In this review, we summarize recent advances in the application of novel functionalized materials in sample preparation for phosphoproteomes and glycoproteomes analysis. In addition, this review specifically discusses the design and preparation of functionalized materials based on different enrichment mechanisms, and proposes research directions and potential challenges for proteomic PTMs research.

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“…About 50%–80% of glycosylation is involved in cellular processes in life activities, and protein glycosylation can be expressed as N ‐linked glycosylation and O ‐linked glycosylation in most cases 3 . It has been shown that N ‐glycosylation plays a crucial role in the regulation of various cellular functions and properties of proteins, including cell–cell communication, cell‐matrix interactions, and immune responses 4–6 . Abnormal protein glycosylation has been found to be involved in a series of negative health effects, including cancer, blood, and lung diseases 7,8 .…”

Section: Introductionmentioning

confidence: 99%

“…3 It has been shown that Nglycosylation plays a crucial role in the regulation of various cellular functions and properties of proteins, including cell-cell communication, cell-matrix interactions, and immune responses. [4][5][6] Abnormal protein glycosylation has been found to be involved in a series of negative health effects, including cancer, blood, and lung diseases. 7,8 Therefore, the analysis of the composition, abundance, and structure of glycopeptides and polysaccharides can help us understand the role of polysaccharides in biological functions and find the potential biomarkers of diseases, so as to provide useful help in clinical diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Hydrophilic, dual amino acid–functionalized zinc sulfide quantum dot for specific identification of N‐glycopeptides from biological samples

Feng

Xie

Liang

et al. 2022

Rapid Comm Mass Spectrometry

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translational modifications, and N-glycosylation plays a crucial role in life activities.Mass spectrometry (MS) has been a powerful technique in the analysis of protein glycosylation. However, the direct detection of glycoproteins in biological samples based on MS still suffers from huge challenges. Therefore, enrichment and purification of samples before MS analysis is an essential prerequisite.Methods: Hydrophilic interaction liquid chromatography (HILIC) has significantly developed for selective enrichment of glycopeptides due to its simple operation process and unbiased enrichment. Herein, hydrophilic, dual amino acidfunctionalized zinc sulfide quantum dots (ZnS QDs) were prepared to enrich glycopeptides using an easy procedure. The enriched glycopeptides were detected using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Results:The obtained material exhibited high selectivity (1:2000), low detection limit (0.1 fmol/μl), good repeatability (10 times), and excellent recovery (89.8%) in glycopeptide enrichment. In the actual application in biological samples, 71 Nglycopeptides and 161 N-glycopeptides were detected from human saliva and serum, respectively.Conclusions: ZnS-Au-GC was successfully prepared using an easy method. The results showed that the obtained material exhibited excellent performance in glycopeptide enrichment. Furthermore, it had showed great potential for glycopeptide enrichment in complex biological samples.

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Porous graphene oxide/chitosan beads with honeycomb-biomimetic microchannels as hydrophilic adsorbent for the selective capture of glycopeptides

Cited by 20 publications

References 35 publications

Recent Developments in Chitosan-Based Adsorbents for the Removal of Pollutants from Aqueous Environments

Recent Developments in Chitosan-Based Adsorbents for the Removal of Pollutants from Aqueous Environments

Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

Hydrophilic, dual amino acid–functionalized zinc sulfide quantum dot for specific identification of N‐glycopeptides from biological samples

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