Porous Silicon Application Survey

Canham, Leigh

doi:10.1007/978-3-319-04508-5_74-1

Cited by 6 publications

(6 citation statements)

References 48 publications

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“…Glutathione-S-transferases immobilized onto porous silicon multilayer thin films resulted in enhanced enzyme function in contrast to that observed for the enzyme free in solution [32]. Further interest in PSi materials by the scientific community has been shown due to its compatibility with chip-based technologies, easy fabrication, tunable properties and multidisciplinary applications [33][34][35][36][37]. Due to their high surface area and photoluminescence nature in the visible region they can serve for a vast array of applications including chemical [38][39][40] and biological sensors [41,42] as well as optoelectronics devices [43].…”

Section: Introductionmentioning

confidence: 99%

Biogenic porous silica and silicon sourced from Mexican Giant Horsetail (Equisetum myriochaetum) and their application as supports for enzyme immobilization

Sola-Rabada

Sahare

Hickman

et al. 2018

Colloids and Surfaces B: Biointerfaces

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Porous silica-based materials are attractive for biomedical applications due to their biocompatibility and biodegradable character. In addition, inorganic supports such as porous silicon are being developed due to integrated circuit chip compatibility and tunable properties leading to a wide range of multidisciplinary applications. In this contribution, biosilica extracted from a rarely studied plant material (Equisetum Myriochaetum), its conversion to silicon and the potential for both materials to be used as supports for enzyme immobilization are investigated. E. myriochaetum was subject to conventional acid digestion to extract biogenic silica with a% yield remarkably higher (up to 3 times) than for other Equisetum sp. (i.e. E. Arvense). The surface area of the isolated silica was ∼400 m/g, suitable for biotechnological applications. Biogenic silicon was obtained by magnesiothermic reduction. The materials were characterized by SEM-EDX, XRD, FT-IR, ICP-OES, TGA and BET analysis and did not contain significant levels of class 1 heavy elements (such as Pb, Cd, Hg and As). Two commercial peroxidases, horseradish peroxidase (HRP) and Coprinus cinereus peroxidase (CiP) were immobilized onto the biogenic materials using three different functionalization routes: (A) carbodiimide, (B) amine + glutaraldehyde and (C) amine + carbodiimide. Although both biogenic silica and porous silicon could be used as supports differences in behaviour were observed for the two enzymes. For HRP, loading onto biogenic silica via the glutaraldehyde immobilization technique (route B) was most effective. The loading of CiP showed a much higher peroxidase activity onto porous silicon than silica functionalized by the carbodiimide method (route A). From the properties of the extracted materials obtained from Equisetum Myriochaetum and the immobilization results observed, these materials appear to be promising for industrial and biomedical applications.

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Section: Introductionmentioning

confidence: 99%

Biogenic porous silica and silicon sourced from Mexican Giant Horsetail (Equisetum myriochaetum) and their application as supports for enzyme immobilization

Sola-Rabada

Sahare

Hickman

et al. 2018

Colloids and Surfaces B: Biointerfaces

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“…To date, PSi has gained popularity in a wide variety of areas including microelectronics, optics, optoelectronics, sensors, solar cells, catalysis, filtration, medical and therapeutic fields due to its particular structure and outstanding properties [1][2][3][4][5][6][7]. Of all these features, large surface to volume ratio (up to 600 m 2 /cm 3 ), high surface reactivity, controllable morphology and pore diameter, biocompatibility, biodegradability, and compatibility with the existing microelectronic and microfluidic technology suggest that PSi holds promise for biomedical applications such as in vivo imaging, tissue engineering, drug delivery, and especially sensing and molecular screening [1][2][3][4][8][9][10][11][12]. By using PSi in sensing application, the large surface area along with the high surface reactivity of this structure results in the high sensitivity and low detection limit.…”

Section: Introductionmentioning

confidence: 99%

A novel approach for osteocalcin detection by competitive ELISA using porous silicon as a substrate

Rahimi

Arough

Yaghoobi

et al. 2017

Biotech and App Biochem

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In this study, porous silicon (PSi) was utilized instead of prevalent polystyrene platforms, and its capability in biomolecule screening was examined. Here, two types of porous structure, macroporous silicon (Macro-PSi) and mesoporous silicon (Meso-PSi), were produced on silicon wafers by electrochemical etching using different electrolytes. Moreover, both kinds of fresh and oxidized PSi samples were investigated. Next, osteocalcin as a biomarker of the bone formation process was used as a model biomarker, and the colorimetric detection was performed by competitive enzyme-linked immunosorbent assay (ELISA). Both Macro-PSi and Meso-PSi substrates in the oxidized state, specifically the Meso-porous structure, were reported to have higher surface area to volume ratio, more capacitance of surface-antigen interaction, and more ability to capture antigen in comparison with the prevalent platforms. Moreover, the optical density signal of osteocalcin detected by the ELISA technique was notably higher than the common platforms. Based on the findings of this study, PSi can potentially be used in the ELISA to achieve better results and consequently more sensitivity. A further asset of incorporating such a nanometer structure in the ELISA technique is that the system response to analyte concentration could be maintained by consuming lower monoclonal antibody (or antigen) and consequently reduces the cost of the experiment.

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“…Consequently, it can be used for biological and medical applications and even cosmetic treatments [12] if desirable optical and luminescent properties can be achieved at low enough cost.…”

Section: Introductionmentioning

confidence: 99%

“…PSi is a biocompatible material [ 10 ] now under clinical evaluation as a therapeutic biomaterial [ 11 ]. Consequently, it can be used for biological and medical applications and even cosmetic treatments [ 12 ] if desirable optical and luminescent properties can be achieved at low enough cost.…”

Section: Introductionmentioning

confidence: 99%

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Luminescence of mesoporous silicon powders treated by high-pressure water vapor annealing

et al. 2012

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We have studied the photoluminescence of nanocrystalline silicon microparticle powders fabricated by fragmentation of PSi membranes. Several porosities were studied. Some powders have been subjected to further chemical etching in HF in order to reduce the size of the silicon skeleton and reach quantum sizes. High-pressure water vapor annealing was then used to enhance both the luminescence efficiency and stability. Two visible emission bands were observed. A red band characteristic of the emission of Si nanocrystals and a blue band related to localized centers in oxidized powders. The blue band included a long-lived component, with a lifetime exceeding 1 sec. Both emission bands depended strongly on the PSi initial porosity. The colors of the processed powders were tunable from brown to off-white, depending on the level of oxidation. The surface area and pore volume of some powders were also measured and discussed. The targeted applications are in cosmetics and medicine.

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Porous Silicon Application Survey

Cited by 6 publications

References 48 publications

Biogenic porous silica and silicon sourced from Mexican Giant Horsetail (Equisetum myriochaetum) and their application as supports for enzyme immobilization

Biogenic porous silica and silicon sourced from Mexican Giant Horsetail (Equisetum myriochaetum) and their application as supports for enzyme immobilization

A novel approach for osteocalcin detection by competitive ELISA using porous silicon as a substrate

Luminescence of mesoporous silicon powders treated by high-pressure water vapor annealing

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