Porous β-Ca2SiO4 ceramic scaffolds for bone tissue engineering: In vitro and in vivo characterization

3D printed porous β-Ca2SiO4scaffolds derived from preceramic resin and their physicochemical and biological properties

“…Previous studies confirmed the good cytocompatibility for β-Ca 2 SiO 4 materials [18,21,22]. Our study demonstrated that β-Ca 2 SiO 4 scaffolds derived from preceramic polymer and CaCO 3 active filler were able for cell adhesion, proliferation, and differentiation.…”

“…β-Ca 2 SiO 4 ceramic is one of the bioactive ceramics [18] and can significantly induce the formation of hydroxyapatite layer on its surface in simulated body fluid (SBF) [19,20], showing the excellent bioactivity. Dai et al [18] prepared porous β-Ca 2 SiO 4 by sol–gel method, which showed good mineralization ability and cytocompatibility. Gou et al [21–23] reported that β-Ca 2 SiO 4 had a moderate degradation, and the dissolved ions could enhance the proliferative response of fibroblasts.…”

“…To date, β-Ca 2 SiO 4 scaffolds were prepared by conventional methods such as polyurethane foam templating [18] and porogen templating [30], which were not easy to control porous scaffolds with well pore interconnection, proper pore size, or high porosity [31,32]. 3D printing technique can control the architectures of porous scaffolds via computer-assisted design or computer-aided manufacturing.…”

An in vivo comparative study of the gelatin microtissue‐based bottom‐up strategy and top‐down strategy in bone tissue engineering application

“…Rat BMSCs were isolated and expanded in culture medium by previous methods . Briefly, Sprague Dawley rats aged 5–7 days were sacrificed with their femurs and tibiae collected in petri dish.…”

Biomimetic Growth of Hydroxyapatite on Kenaf Fibers

“…The most commonly explored porous bone scaffold materials include bioceramics and bioactive glass (Chen et al 2013;Chen et al 2014) and polymers (Owen et al 2016). Plus there are many kinds of biocompatible materials have been used to guide mineralization of HA to make them suitable as bone repair materials, including ceramics (Dai et al 2015), metallics , polymeric materials (Huang et al 2015), and their composites (Guo et al 2015), cellulose (Li et al 2012;Morimune-Moriya et al 2015), and collagen (Tomoaia and Pasca 2015).…”