Position Statement of Transplant Activity in the Middle East in Era of COVID-19 Pandemic

Zidan, Ahmed; Alabbad, Saleh; Ali, Tariq; Nizami, Imran; Haberal, Mehmet; Tokat, Yaman; Kamel, Rabab; Said, Hazem; Abdelaal, Amr; ElSharkawy, Magdy; Fouly, Amr El; Sayed, Hatem; Al-Mousawi, M; Alghonaim, Mohammed; Bröering, Dieter C.

doi:10.1097/tp.0000000000003348

Cited by 12 publications

(14 citation statements)

References 1 publication

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“…Most government and university centres have temporarily discontinued transplant activities based on an unacceptable donor risk, uncertain data on the impact of COVID-19 on recipients, and to reserve resources to manage the pandemic. 7 At our centre, although operations were temporarily restricted, outpatient clinics and follow-up continued. Our staff followed up recipients using telemedicine and/or hospital visits as needed.…”

Section: Discussionmentioning

confidence: 96%

“…During the pandemic, the Ministry of Health in Egypt increased medical health service capacity and assigned 23 hospitals to manage COVID-19 in each governorate as quarantine hospitals. 7 Ain Shams University Hospital (ASCOT) temporarily held an LDLT programme from 2 March to 13 July 2020. Most government and university centres have temporarily discontinued transplant activities based on an unacceptable donor risk, uncertain data on the impact of COVID-19 on recipients, and to reserve resources to manage the pandemic.…”

Section: Discussionmentioning

confidence: 99%

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Repeated COVID-19 infection in recipients of post-living donor liver transplantation: Two real-life cases

Montasser¹,

Dabbous²,

Salah³

et al. 2021

Journal of Liver Transplantation

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Repeated COVID-19 infection in recipients of post-living donor liver transplantation: Two real-life cases

Montasser¹,

Dabbous²,

Salah³

et al. 2021

Journal of Liver Transplantation

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“…Inpatient management of transplant patients with COVID-19 was as follows: discontinuation of antimetabolites (both mycophenolate mofetil and azathioprine) and continuation of CNIs, except if patients required ventilation with a severe pneumonia. The interleukin-6 inhibitor, tocilizumab, was considered to treat severe cytokine release symptoms [ 9 ••].…”

Section: Transplant Centers’ Responses By Regionmentioning

confidence: 99%

“…Around the world, transplant centers made individualized decisions about the conduct of their programs, though several themes were mostly consistent: pre-operative testing of recipients and donors for COVID-19 infection, minimizing immunosuppression, rigorous limited recipient selection, and the use of telemedicine in the outpatient setting when possible [ 1 ••, 3 , 5 , 8 , 9 ••]. In this paper, we explore the variations on these management strategies, to demonstrate that the transplant center response to the COVID-19 pandemic developed to address the individual needs of the centers, but ultimately reflected the desire to protect patients from any modifiable excessive harm.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient

et al. 2021

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Purpose of the Review In response to the COVID-19 pandemic, vulnerable populations, such as transplant patients, were at greater risk than the regular population. In order to protect these populations, transplant centers enacted new guidelines. We approach this review by looking at how different transplant regions responded to COVID-19 and analyze the unifying themes that have proven invaluable in the subsequent waves. Recent Findings We noticed that most elective surgeries including living donor transplant operations were suspended in most countries. The response to deceased donor transplants varied between countries: in some deceased donor transplants continued with modified donor and recipient criteria, while in other countries this surgery was suspended. There was a general trend of decreasing or holding antimetabolites, treating the virus with hydroxychloroquine and/or azithromycin, and converting outpatient clinics to virtual clinics. Summary We learned how to carefully select donors and recipients, tailor immunosuppressant regiments, and implement telemedicine. The kidney recipient population can be effectively managed in times of crisis with appropriate accommodations and measures. This review can be a model for the transplant community for future pandemics.

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“…Prime Minister Shinzo Abe declared a state of emergency in seven urban areas in Japan on April 7 and extended it until May 25. Previous studies reported a strong temporal association between the increase in COVID-19 infections and a marked overall decrease in solid-organ transplantation procedures and procurement in Europe, USA, and the Middle East (Loupy et al 2020 ; Dominguez-Gil et al 2020 ; Zidan et al 2020 ). A recent study reported methods for donor selection for solid organ transplantation during the pandemic (Galvan et al 2020 ).…”

Section: Introductionmentioning

confidence: 97%

Management of regional bone bank during declaration of a state of emergency concerning the COVID-19 in Japan

et al. 2021

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Bone banks are necessary for providing biological allografts for a series of orthopedic procedures. As nations cope with new realities driven by the 2019 coronavirus disease (COVID-19) pandemic, health-care providers, institutions, and patients share a particular concern about the effect of COVID-19 on organ donation and transplantation. Here, we describe the management of the Kitasato University Bone Bank during the state of emergency declared in response to COVID-19. Living donors received pre-operative screening by PCR, and allograft bone from COVID-19-negative donors was cryopreserved as transplantable tissues. The weekly rate of infection gradually increased from February 2–9 to April 5–11 in the dead donor-derived allograft bone-harvesting region covered by the Bank. It is becoming clear that the virus can be transmitted by asymptomatic patients, and that this route may have facilitated the spread of COVID-19. Therefore, the Bank stopped dead donor donation to consider the safety of medical staff. Three recipients received bone allografts following pre-operative COVID-19 screening by PCR. All patients were asymptomatic after bone allograft. Our experience may provide helpful information for the management of tissue banks.

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Position Statement of Transplant Activity in the Middle East in Era of COVID-19 Pandemic

Cited by 12 publications

References 1 publication

Repeated COVID-19 infection in recipients of post-living donor liver transplantation: Two real-life cases

Repeated COVID-19 infection in recipients of post-living donor liver transplantation: Two real-life cases

COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient

Management of regional bone bank during declaration of a state of emergency concerning the COVID-19 in Japan

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