Management of regional bone bank during declaration of a state of emergency concerning the COVID-19 in Japan

Uchida, Kentaro; Mukai, Manabu; Miyagi, Masayuki; Fukushima, Kazuhiko; Uchiyama, Katsufumi; Nakayama, Akiko; Matsumoto, Mai; Takahira, Naonobu; Urabe, Ken; Takaso, Masashi; Inoue, Gen

doi:10.1007/s10561-021-09908-w

Cited by 5 publications

(3 citation statements)

References 16 publications

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“…Therefore, tissue banks all over the world established strict preventive measures, or in some cases stopped collecting samples. On the other hand, at the moment, no documented reports have proved any COVID-19 infection following tissue transplantation [ 20 , 21 ]. We think that our results could represent a valid basis for further studies related to the possibility of bone donation in patients who suffered and healed from COVID-19.…”

Section: Discussionmentioning

confidence: 99%

Detection of SARS-CoV-2 in Cancellous Bone of Patients with COVID-19 Disease Undergoing Orthopedic Surgery: Laboratory Findings and Clinical Applications

Guazzoni

Castelli

Polizzi

et al. 2022

IJERPH

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An emerging issue for orthopedic surgeons is how to manage patients with active or previous COVID-19 disease, avoiding any major risks for the surgeons and the O.R. personnel. This monocentric prospective observational study aims to assess the prevalence of SARS-CoV-2 viral RT-PCR RNA in cancellous bone samples in patients with active or previous COVID-19 disease. We collected data about 30 consecutive patients from our institution from January 2021 to March 2021 with active or previous COVID-19 disease. The presence of SARS-CoV-2 in the samples was determined using two different PCR-based assays. Eighteen of the thirty patients included in the study had a positive nasopharyngeal swab at the time of surgery. Twelve patients had a negative nasopharyngeal swab with a mean days since negativization of 138 ± 104 days, ranging from 23 to 331 days. Mean days of positivity to the nasal swab were 17 ± 17. Twenty-nine out of thirty (96.7%) samples were negative for the presence of SARS-CoV-2 RNA. In one sample, low SARS-CoV-2 load (Cycle threshold (Ct) 36.6.) was detected but not confirmed using an additional confirmatory assay. The conducted study demonstrates the absence of the viral genome within the analyzed cancellous bone. We think that the use of personal protection equipment (PPE) to only protect from aerosol produced during surgery, both in active and recovered patients, is not strictly necessary. We think that the use of PPE should not be employed by surgeons and the O.R. personnel to protect themselves from aerosols produced from the respiratory tract. Moreover, we think that our results could represent a valid basis for further studies related to the possibility of bone donation in patients that suffered and recovered from COVID-19.

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Section: Discussionmentioning

confidence: 99%

Detection of SARS-CoV-2 in Cancellous Bone of Patients with COVID-19 Disease Undergoing Orthopedic Surgery: Laboratory Findings and Clinical Applications

Guazzoni

Castelli

Polizzi

et al. 2022

IJERPH

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“…As a result, the bank stopped accepting donations from deceased donors in order to protect medical personnel. Following bone allograft, none of the patients had any symptoms [ 32 ]. The same requires to be followed in our country if such a pandemic strikes in our part of the country too.…”

Section: Reviewmentioning

confidence: 99%

Need, Strategies and Requirements in the Medical System for Bone Banks: A Review Article

Verma¹,

Anjankar²,

Singh³

2022

Cureus

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An orthopedic bone bank's creation and management is a challenging procedure where medical organization and legal requirements interact. There are no formal regulations for the management and organization of an orthopedic bone bank in the Netherlands or any other nation in Europe. The recently revised "law of security and quality for utilizing human materials in the Netherlands establishes guidelines for the technical and administrative elements of using human tissue and cells. The bone bank's processes involve a rigorous questionnaire for choosing donors, a complete bacteriological, histological, and serological examination, as well as industry-standard, practices for registering, processing, preserving, distributing, and storing bone allografts. This article explains how an approved bone bank is run, and it may be used as a suggestion for formal regulation or as a model for additional orthopedic bone banks in Europe. Osseous graft manufacture, testing, packing, storage, and transportation are all handled by bone banks. Their primary responsibility is to guarantee the transplants' biological characteristics and microbial cleanliness by legal and quality criteria. All orthopedic surgeons face the challenge of reconstructing bone defects; to address this issue, there are several methods, including the use of autografts, allografts, and bone substitutes to enhance and speed bone recovery. Although autografts have superior biological qualities, their volume is constrained and they are linked to donor site morbidity. Allografts are readily accessible, however, there are still worries about the possibility of infections, and they lack osteosarcoma qualities.

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“…A literature review of nursing students’ attitudes found that interest in organ donation correlated with an increase in donor cards [ 21 ]. The Kitasato Bone Bank ceased donations until protocols for COVID-19 screening were implemented [ 22 ], suggesting a potential impact on other organ and tissue donation processes. Additionally, a study conducted at a Baptist hospital reported that religion appeared to provide comfort and relief for donor relatives [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Japanese Perception of Organ Donation and Implications for New Medical Technologies: Quantitative and Qualitative Social Media Analyses

Vargas Meza,

Oikawa

2024

JMIR Form Res

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Background:The Rapid Autopsy Program (RAP) is a useful procedure to understand human biology and illnesses such as cancer. However, implementing RAP in Japan requires understanding good death and incorporating socio-cultural aspects. By revising perceptions of organ donation in social media, we can shed light on the issues of implementing new medical research procedures such as RAP. Objective:We examined YouTube and Twitter to uncover actors and quality of organ donation communication, providing recommendations to implement new medical research procedures. Methods:Using the term "????"(organ donation), we collected data from YouTube and Twitter, classifying it into five dimensions: time, individuality, place, activity, and relations. We employed a scale to assess the quality of organ donation information, and divided YouTube videos into three groups to understand their differences through statistical analysis. We also conducted a text-based analysis of narratives tied to donation.Results: Most YouTube videos were uploaded in 2021 (189/638, 29.62%) and 2022 (165, 25.86%), while Tweets peaked between 2019 and 2022. Citizens (184/770, 23.89%), media (170, 22.07%) and unknown actors (121, 15.71%) uploaded most videos about organ donation, whereas most identified users in a sample of 100 average retweeted Tweets were citizens (70.32%), as well as in average liked Tweets (68.42%). Information quality in Hokkaido (F(2.46, 147.74) = [5.28], p = .005) and Kyushu and Okinawa (F(2.46, 147.74) = [5.28], p = .005) was high, whereas most mentioned countries in Twitter were Japan and China. Information videos versed on borrowed life and requests to register as donor, while No Information and Misinformation videos mostly contained organ trafficking accusations by American media. Tweets were mostly about donation intention statements and family consent. Most video hyperlinks pointed to YouTube and Twitter, whereas most Twitter hyperlinks pointed to news reports by Japanese media. Conclusions:There is a high likelihood of implementing new medical research procedures such as RAP in Japan. Recommendations include the conceptualization of research data as borrowed data, horizontal and diversified management of donation programs, and paying attention to science misinformation trends and popular culture trends.

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Management of regional bone bank during declaration of a state of emergency concerning the COVID-19 in Japan

Cited by 5 publications

References 16 publications

Detection of SARS-CoV-2 in Cancellous Bone of Patients with COVID-19 Disease Undergoing Orthopedic Surgery: Laboratory Findings and Clinical Applications

Detection of SARS-CoV-2 in Cancellous Bone of Patients with COVID-19 Disease Undergoing Orthopedic Surgery: Laboratory Findings and Clinical Applications

Need, Strategies and Requirements in the Medical System for Bone Banks: A Review Article

Japanese Perception of Organ Donation and Implications for New Medical Technologies: Quantitative and Qualitative Social Media Analyses

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