Mood (i.e., our current background affective state) often unobtrusively yet pervasively affects how we think and behave. Typically, theoretical frameworks position it as an embodied source of information (i.e., a biomarker), activating thinking patterns that tune our attention, perception, motivation, and exploration tendencies in a context-dependent manner. Growing behavioural and electrophysiological research has been exploring the mood–language interactions, employing numerous semantics-oriented experimental paradigms (e.g., manipulating semantic associations, congruity, relatedness, etc.) along with mood elicitation techniques (e.g., affectively evocative film clips, music, pictures, etc.). Available behavioural and electrophysiological evidence has suggested that positive and negative moods differently regulate the dynamics of language comprehension, mostly due to the activation of mood-dependent cognitive strategies. Namely, a positive mood has been argued to activate global and heuristics-based processing and a negative mood – local and detail-oriented processing during language comprehension. Future research on mood–language interactions could benefit greatly from (i) a theoretical framework for mood effects on semantic memory, (ii) measuring mood changes multi-dimensionally, (iii) addressing discrepancies in empirical findings, (iv) a replication-oriented approach, and (v) research practices counteracting publication biases.