2020
DOI: 10.1016/j.cca.2020.03.009
|View full text |Cite
|
Sign up to set email alerts
|

Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

9
539
6
31

Year Published

2020
2020
2023
2023

Publication Types

Select...
7
2

Relationship

0
9

Authors

Journals

citations
Cited by 538 publications
(585 citation statements)
references
References 5 publications
9
539
6
31
Order By: Relevance
“…The E gene PCR was sufficient to diagnose a SARS-CoV-2 infection but the RdRp protocol was recommended to confirm a positive result [22 , 23] . The overall positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan was 38% [24] . The positive rate of PCR for oropharyngeal swabs is not very high: only 53.3% of COVID-19-confirmed patients had positive oral swabs tests [25] .…”
Section: Diagnosismentioning
confidence: 96%
“…The E gene PCR was sufficient to diagnose a SARS-CoV-2 infection but the RdRp protocol was recommended to confirm a positive result [22 , 23] . The overall positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan was 38% [24] . The positive rate of PCR for oropharyngeal swabs is not very high: only 53.3% of COVID-19-confirmed patients had positive oral swabs tests [25] .…”
Section: Diagnosismentioning
confidence: 96%
“…And a study reported that the positive rate of the testing was only 30-50% in clinical application. 9,28 The sequencing technology of the viral had elevated the accuracy of detection results, but it needed high-quality laboratory requirement which could only be provided for supplementary evidence. Rapid antibody detection often lagged behind the nucleic acid detection due to the presence of the window period.…”
Section: Complementarity With Other Analytical Techniquesmentioning
confidence: 99%
“…Many techniques use molecules that interact with the virus RNA genome or the reverse transcribed DNA, either for clinical testing, diagnosis or determination of viral loads. PCR primers and RT-qPCR probes are been used to detect the SARS-CoV-2 (e.g., [8][9][10][11]) using molecular biology techniques. It is likely that oligonucleotides complementary to the virus RNA will be tested as possible antiviral agents [12,13].…”
Section: Introductionmentioning
confidence: 99%