Possibilities of urolithiasis crystallodiagnostics

Abstract

Nowadays, one of the most common groups of diseases in veterinary medicine is the urinary system pathology. Urolithiasis is widespread disease, could be found in many species, including cats, dogs, rabbits, guinea-pigs, turtles etc. Despite the large scale of this pathology in animal world, there are some challenges with diagnostic process and diagnosis's verification. The aim of our study is estimation of diagnostic value of advanced urine tesiocrystalloscopy in urolithiasis (by the example of cats). We studied crystallogenic and initiated properties of 24 healthy cats and 32 animals with urolithiasis. Own and initiated crystallogenesis of the urine specimens was studied. For teziographic test we used sodium chloride solution (0.45%, 0.9%, 3% consequently), hydrochloric acid solution (0.1H) and sodium hydroxide (0.1H) as a crystal-forming substances. We used the original criterions to estimate crystalloscopic and tezigraphic facias. As the main parameters structure index (SI), crystallizability (Cr), facia's destruction degree (FDD) and edge belt intensity (EB) were used to describe free crystallogenesis, and main tezigraphic coefficient (Q), belt coefficient (B) and FDD were used for the comparative tezigraphy data. Results showed that Cat's urine in normal conditions has moderate crystallogenic activity, but in urolithiasis it acquires high level of crystallizing, with intermedium value of structure index, and significant destruction of crystal-forming elements. A similar changes of physical-chemical biomedium properties are detected during analysis of tezigraphic microslides of urines of cats with urolithiasis, that was prepared using 0.9% sodium chloride as basis substance. In conclusion, we fixed that tesiocristalloscopic "pattern" of cats' urine in urolithiasis significantly transforms into activation of crystal formation and increasing of biomedium's initiating potential. So, the investigation of free or initialized urine crystallization in urolithiasis has diagnostic value.

Study of Struvite Crystals and Dietary at Risk for the Formation of Struvite Urolithiasis in Dogs in Small Animal Practices

“…Beberapa tanda klinis urolitiasis pada anjing meliputi ischuria, polakiuria, hemoglobinuria, leukosituria, proteinuria, kristaluria, dan yang paling sering ditemukan adalah hematuria dan dysuria (Martusevich & Kozlova, 2017). Penelitian yang dilaporkan oleh Fromsa dan Saini (2019), dari 23 anjing yang mengalami urolitiasis, hanya tujuh anjing yang ditemukan kristaluria (30.4%).…”

Protective effect of Urtica dioica in liver and kidney damages induce by ethylene glycol in rabbits: A histopathological study

“…formation of stones in the urinary tract). Often, CaOxinduced oxidative stress (4,5). As time progresses, we become more aware of what nature contains as beneficial to our health, and with it our desire to learn more about these elements, one of these ancient elements in its existence, which has been talked about in recent research is the Stinging Nettle (Urtica dioica) has been a staple in herbal medicine since ancient times (6).…”

Effect of commercial medicinal feeds on the physical and chemical properties of urine

“…Clinical studies have shown that dilution of urine has a positive effect on the prevention and treatment of urolithiasis. Dilution of urine helps reduce the concentration of precursors [7,8]. Dilution of urine is achieved by increasing the frequency of diuresis, thereby reducing the residence time of mineral compounds in the bladder.…”