Possible Association of Papillophlebitis with Guillain-Barré Syndrome: Case Report

Abstract

In this case report, we presented a patient with visual deterioration as a result of papillophlebitis in the right eye who was later diagnosed with Guillain-Barré syndrome (GBS). Upon systemic and laboratory work-up to determine the etiology of papillophlebitis, the diagnosis of GBS was made and treatment was initiated immediately. The ocular and systemic symptoms resolved quickly after starting intravenous immunoglobulin therapy. We present this case to emphasize the importance of etiological diagnosis in papillophlebitis and the unusual presentation of GBS.

Epidemiologie okulärer Manifestationen bei Autoimmunkrankheiten

“…Akkommodationsinsuffizienz und Ptosis können, auch wenn keine Ophthalmoplegie vorliegt, auf ein zugrunde liegendes Guillain-Barré-Syndrom hinweisen [64]. Die Papillophlebitis wurde auch als erste Manifestation der Krankheit dokumentiert, die zu schwerwiegenden Komplikationen wie Blutungen des Sehnervs, Makulaödemen und Watteflecken führen kann [65].…”

Epidemiology of Ocular Manifestations in Autoimmune Disease

“…Accommodation insufficiency and ptosis, even in the absence of ophthalmoplegia, can indicate underlying Gullain-Barre syndrome ( 64 ). Papillophlebitis has also been documented as an initial disease manifestation that can lead to serious complications, such as haemorrhage of the optic nerve, macular oedema and cotton wool spots ( 65 ).…”