Possible involvement of thiamine insufficiency in heart failure in the institutionalized elderly

Mei, Ao; Yamamoto, Koudai; Ohta, Junko; Abe, Yasusei; Niki, Naho; Inoue, Shino; Tanaka, Shinzo; Kuwabara, Akiko; Miyawaki, Takashi; Tanaka, Kiyoshi

doi:10.3164/jcbn.18-85

Cited by 6 publications

(3 citation statements)

References 22 publications

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“…4). (65) The subjects in the current study were not severely vitamin B 1 deficient, but blood vitamin B 1 level was a significant risk factor for heart failure independent of age, BMI, and renal function. With the ageing society, the prevalence of elderly heart failure is rapidly increasing, and has become a serious societal problem.…”

Section: Vitamin Bmentioning

confidence: 61%

Insufficiency of B vitamins with its possible clinical implications

Tanaka

Mei

Kuwabara

2020

J. Clin. Biochem. Nutr.

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Vitamin deficiency causes classical deficiency diseases such as beriberi and rickets. Vitamin insufficiency, which is milder than deficiency, is a risk for various chronic diseases, but its significance has not been recognized in Japan. Vitamin D insufficiency is quite common in Japan, and a serious risk for osteoporotic fracture through its unbeneficial effect on bone and muscle. Insufficiency of B vitamins has been little studied. However, hyperhomocysteinemia caused by the insufficiency of vitamin B 12 or folate is a risk for cardiovascular disease, osteoporotic fracture, and cognitive impairment. Additionally, we have recently reported that vitamin B 1 insufficiency is a risk for heart failure in the elderly. The effect of improvement of nutritional status including vitamins is less marked compared to drug treatment, but it costs far less, and is suited for the primary prevention of diseases. Randomized controlled trial is considered the study with the most robust evidence in the evaluation of drug treatment, but more emphasis should be put on the well-designed cohort studies in evaluating the role of nutrients. Vitamin insufficiency is quite prevalent, and vitamin requirement is much higher for its prevention than for the prevention of deficiency.

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Section: Vitamin Bmentioning

confidence: 61%

Insufficiency of B vitamins with its possible clinical implications

Tanaka

Mei

Kuwabara

2020

J. Clin. Biochem. Nutr.

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“…4,5) The decrease in whole blood thiamine concentration was associated with an increased level of brain natriuretic peptide, suggesting that the decrease in thiamine concentration may increase the risk of HF. 6) Additionally, diuretics have been identified as the main cause of thiamine deficiency in patients with cardiovascular diseases. 7) Basically, the association between thiamine deficiency and cardiovascular system disorders remains not fully understood and controversial.…”

Section: Article P271mentioning

confidence: 99%

Characteristics of Shoshin Beriberi, a Fulminant Cardiovascular Type of Beriberi

Amiya,

Morita

2024

Int. Heart J.

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“…With the ageing society, the prevalence of elderly heart failure is rapidly increasing, and has become a serious societal problem. It was considered likely that VB1 insufficiency is a modifiable risk factor for elderly heart failure, and VB1 can play an important role both clinically and societally for its primary prevention (9).…”

Section: Clinical and Societal Implications Of Vitamin Insufficiencymentioning

confidence: 99%

Role of Vitamins and Minerals in Health and Diseases

Tanaka

Taketani

Angeles‐Agdeppa

et al. 2022

J Nutr Sci Vitaminol

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We have adopted the following four topics: 1) dietary phosphorus management in chronic kidney disease (CKD) patients, 2) inadequate nutrient intakes in Filipino schoolchildren and adolescents, 3) clinical and societal implications of vitamin insufficiency, and 4) zinc transporters. Vitamins and minerals play essential roles in health promotion in clinical and societal perspectives with marked advances in understanding the mechanism underlying such effects.

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Possible involvement of thiamine insufficiency in heart failure in the institutionalized elderly

Cited by 6 publications

References 22 publications

Insufficiency of B vitamins with its possible clinical implications

Insufficiency of B vitamins with its possible clinical implications

Characteristics of Shoshin Beriberi, a Fulminant Cardiovascular Type of Beriberi

Role of Vitamins and Minerals in Health and Diseases

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