Post COVID-19 cerebral venous sinus thrombosis; a case report

Ahmad, Shwan A.; Kakamad, Fahmi H.; Mohamad, Hemin S.; Salih, Bestoon Kh; Mohammed, Shvan H.; Abdulla, Berwn A.; Salih, Abdulwahid M.

doi:10.1016/j.amsu.2021.103031

Cited by 11 publications

(11 citation statements)

References 17 publications

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“…However, in about 14% of the cases, acute respiratory distress syndrome (ARDS) can develop which is a potentially fatal condition [ 6 ]. ARDS can especially develop in patients predisposed to certain risk factors, such as diabetes mellitus, old age, and hypertension [ 7 ]. COVID-19 is considered a system disease as it can adversely affect various organs, including the cardiovascular, gastrointestinal, nervous, hematopoietic, and cardiovascular systems; however, it is primarily considered a respiratory condition.…”

Section: Introductionmentioning

confidence: 99%

Post COVID-19 pulmonary fibrosis; a meta-analysis study

Amin¹,

Kakamad

Ahmed

et al. 2022

Annals of Medicine &Amp; Surgery

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127

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Section: Introductionmentioning

confidence: 99%

Post COVID-19 pulmonary fibrosis; a meta-analysis study

Amin¹,

Kakamad

Ahmed

et al. 2022

Annals of Medicine &Amp; Surgery

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127

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“…Thus, when combined with mRNA vaccines, a hypercoagulable state could potentially lead to obstruction of the cerebral sinuses when a thrombus does not resolve. It is important to consider that the COVID-19 infection has also been demonstrated to cause a hypercoagulable state and is responsible for a number of CVST’s [ 27 , 28 , 29 ]. The risk of a COVID-19 infection itself may be more likely to cause CVST in comparison to the mRNA vaccines [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use

Frommeyer

Gilbert

et al. 2023

Life

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Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report documents a case of CVST in a 32-year-old female patient who received her second Pfizer mRNA COVID-19 vaccination 16 days prior to hospital admission and had started oral combined contraceptives approximately 4 months beforehand. Clinicians should be cognizant of the possibility that mRNA vaccines, when combined with other risk factors like oral contraceptive pill use, may enhance one’s hypercoagulable status.

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“…Nevertheless, the exact cause of the disease is still unknown in about 30% of CVST patients (20). Recently, many cases of COVID-19 infection causing intracranial venous sinus thrombosis have been reported (21)(22)(23). Endothelial dysfunction occurs during COVID-2019 infection, leading to platelet adhesion, leukocyte aggregation, complement activation, and cytokine release, which results in microvascular thrombosis (24).…”

Section: Discussionmentioning

confidence: 99%

A case report of cerebral venous sinus thrombosis presenting with rapidly progressive dementia

Zhang

Xue

et al. 2022

Front. Med.

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BackgroundCerebral venous sinus thrombosis (CVST) is a rare but serious and treatable cause of neurologic symptoms. Due to the variable clinical presentation, CVST was often misdiagnosed. According to published case reports, common clinical manifestations of CVST include headache, focal neurological deficit, epilepsy, papilledema, etc. It is rare, nevertheless, to mention cases of rapidly progressive dementia (RPD).Case presentationWe reported a case of a 62-year-old retired male accountant, a Han Chinese from eastern China, who initially presented with slow response and memory decline. Until 2 months later, his memory declined and slow response deteriorated significantly, and he could not even complete simple tasks like brushing his teeth, washing his face, washing his feet, and dressing himself, and sometimes developed fecal incontinence. His neuropsychological test demonstrated severe cognitive decline. The cerebrospinal fluid (CSF) studies revealed markedly high opening pressure (260 mm of water), and coagulation tests indicated a mild elevation of D-Dimer of 1.19 mg/L. The magnetic resonance venography (MRV) showed thrombosis of the left transverse sinus, sigmoid sinus, and jugular venous bulb and was diagnosed as CVST. He switched from subcutaneous low molecular weight heparin (LMWH) and transitioned to oral anticoagulants at the time of discharge. The repeated CSF studies revealed normal opening pressure. After 5 days of anticoagulant treatment, his symptoms considerably improved, and a 1-month follow-up revealed that he had fully healed with no signs of recurrence.ConclusionThis case demonstrated the clinical heterogeneity of CVST, which should be taken into account for differential diagnosis of RPD. This case study also offered fresh data for the categorization of the clinical traits and the diagnosis of CVST.

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Post COVID-19 cerebral venous sinus thrombosis; a case report

Cited by 11 publications

References 17 publications

Post COVID-19 pulmonary fibrosis; a meta-analysis study

Post COVID-19 pulmonary fibrosis; a meta-analysis study

Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use

A case report of cerebral venous sinus thrombosis presenting with rapidly progressive dementia

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