Post-extraction bacteraemia: role of antiseptics and antibiotics

Macfarlane, T. W.; Ferguson, M.M.; Mulgrew, Christopher J.

doi:10.1038/sj.bdj.4805302

Cited by 76 publications

(38 citation statements)

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“…Moreover, broad-spectrum degerming rinses, such as povidone-iodine, chloramine-T, and chlorhexidine, have been shown to reduce the incidence of bacteremia when administered as a rinse or irrigation prior to the extraction procedure or instrumentation, and povidoneiodine was shown to be the most potent in reducing the incidence (84,121,127,144).…”

Section: Tooth Extractionmentioning

confidence: 99%

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

et al. 2009

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SUMMARY The human gingival niche is a unique microbial habitat. In this habitat, biofilm organisms exist in harmony, attached to either enamel or cemental surfaces of the tooth as well as to the crevicular epithelium, subjacent to a rich vascular plexus underneath. Due to this extraordinary anatomical juxtaposition, plaque biofilm bacteria have a ready portal of ingress into the systemic circulation in both health and disease. Yet the frequency, magnitude, and etiology of bacteremias due to oral origin and the consequent end organ infections are not clear and have not recently been evaluated. In this comprehensive review, we address the available literature on triggering events, incidence, and diversity of odontogenic bacteremias. The nature of the infective agents and end organ infections (other than endocarditis) is also described, with an emphasis on the challenge of establishing the link between odontogenic infections and related systemic, focal infections.

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Section: Tooth Extractionmentioning

confidence: 99%

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

et al. 2009

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“…MACFARLANE et al [17] have reported that post-extraction bacteremia is best prevented by chlorhexidine administration.…”

Section: Discussionmentioning

confidence: 99%

Effects of Various Antiseptics on Bacteremia Following Tooth Extraction.

Yamalik

Yücetaş

Abbasoğlu

1992

The Journal of Nihon University School of Dentistry

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The effect of local irrigation of the gingival sulcus, which is considered an important source of bacteremia following dental procedures, with three different antiseptic solutions including hydrogen peroxide, chlorhexidine and povidone iodine, on the frequency of bacteremia after tooth extraction was determined, and the efficacies of the three antiseptics were compared. Although all the antiseptic solutions reduced the frequency of bacteremia to various degrees, povidone iodine was the most effective, and seemed to be the best choice since the decrease was statistically significant. Local administration of antiseptic solutions is therefore recommended as an adjuvant to systemic antibiotic prophylaxis.

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“…chlorhexidine and povidone-iodine) used prior to certain dental procedures may reduce the prevalence and severity of bacteraemias. 37,38 The American Heart Association recommend use of local irrigation with chlorhexidine before treatment that can result in a bacteraemia. Whether such a procedure is sufficient to prevent infective endocarditis in either high or moderate risk patients has yet to be determined.…”

Section: Efficacy Of Antibiotic Prophylaxis In the Prevention Of Iementioning

confidence: 99%