Post-process composition and biological responses of laser sintered PMMA and β-TCP composites

Velu, Rajkumar; Kamarajan, Banu Pradheepa; Ananthasubramanian, M.; Ngo, Truc T.; Singamneni, Sarat

doi:10.1557/jmr.2018.76

Cited by 15 publications

(4 citation statements)

References 54 publications

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“…[ 218 ] Therefore, TCP is popular for bone reconstruction and repair applications. The development of TCP composite powder for SLS has been exemplified with poly(methyl methacrylate) (PMMA) [ 219 ] and PEEK, [ 220 ] and can be extended to other polymer matrices.…”

Section: Thermoplastic Powdersmentioning

confidence: 99%

Recent Progress on Polymer Materials for Additive Manufacturing

Tan

Zhu

Zhou

2020

Adv Funct Materials

488

238

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Additive manufacturing (AM) is the process of printing 3D objects in a layer-by-layer manner. Polymers and their composites are some of the most widely used materials in modern industries and are of great interest in the field of AM due to their vast potential for various applications, especially in the medical, aerospace, and automotive industries. Many studies have been conducted to develop new polymer materials for AM techniques, which include vat photopolymerization, material jetting, powder bed fusion, material extrusion, binder jetting, and sheet lamination. Although several reviews on the development of polymer materials for AM have been published, most of them only focus on a specific application, process, or type of material. Therefore, this article serves to provide a comprehensive review on the progress in polymer material development for AM techniques. It begins with an introduction to different AM techniques, followed by highlighting the progress of their development. Material requirements, notable advances in newly developed materials and their potential applications are discussed in detail and summarized. This review concludes by identifying the major challenges currently encountered in using AM for polymer materials and providing insights into the valuable opportunities it presents, in hopes of spurring further development in this field.

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Section: Thermoplastic Powdersmentioning

confidence: 99%

Recent Progress on Polymer Materials for Additive Manufacturing

Tan

Zhu

Zhou

2020

Adv Funct Materials

488

238

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“…= mass of released drug pre − treatment mass of polymer × drug loading (2) where M t represents the cumulative mass of the drug released into the solution by time t, and M o represents the total mass of the drug present inside the polymer sample at time zero. Because the actual drug loading was not possibly determined for the exact same sample that the drug release study was performed on, the initial drug loading, M o , used in Equation (2) was taken from its "twin" sample, which underwent identical 3D printing and scCO 2 treatment processes within the same batch.…”

Section: Drug Release Measurementsmentioning

confidence: 99%

“…To address this limitation, there have been some attempts to apply 3-dimensional (3D) printing technology to prepare the polymer matrix for various biomedical, medical, and pharmaceutical applications, with more flexibility and controllability of material porosity. For example, Velu et al used selective laser sintering to 3D-print PMMA/β-tricalcium phosphate composite for bone repair and replacement applications [2]. Valerga et al applied a fused deposition modeling technique to fabricate a PLA base for implant devices [3].…”

Section: Introductionmentioning

confidence: 99%

Controlled Release of Flurbiprofen from 3D-Printed and Supercritical Carbon Dioxide Processed Methacrylate-Based Polymer

Ngo

Kim

2023

Pharmaceutics

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The ability to engineer and predict drug release behavior during treatment is critical to the design and implementation of effective drug delivery systems. In this study, a drug delivery system consisting of a methacrylate-based polymer and flurbiprofen was studied, and its release profile in a controlled phosphate-buffered saline solution was characterized. The polymer, which was 3D printed and processed in supercritical carbon dioxide under different temperature and pressure settings, showed sustained drug release over a prolonged period. A computer algorithm was used to determine the drug release time duration before reaching steady state and the maximum drug release at steady state. Several empirical models were applied to fit the release kinetic data to gain information about the drug release mechanism. The diffusion coefficients for each system were also estimated using Fick’s law. Based on the results, the influence of supercritical carbon dioxide processing conditions on the diffusion behavior is interpreted, providing insights into the effective and tunable design of drug delivery systems for targeted treatment specifications.

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“…Therefore, TCP is popular for bone reconstruction and repair applications. The development of TCP composite powder for SLS has been exemplified with poly(methyl methacrylate) (PMMA) [152,153] and PEEK [154], and can be extended to other polymer matrices.…”

Section: Nanofillersmentioning

confidence: 99%

Development and optimization of polypropylene-based powders for selective laser sintering

Tan¹

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This thesis contains material from 3 papers published in the following peerreviewed journals in which I am listed as an author.Chapter 2 is published as a section of L.J. Tan, W. Zhu, and K. Zhou. Recent progress on polymer materials for additive manufacturing, Advanced Functional Materials, 2020. p. 2003062. The contributions of the co-authors are as follows:• I reviewed the literature and drafted the manuscript.

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Post-process composition and biological responses of laser sintered PMMA and β-TCP composites

Abstract: Abstract

Cited by 15 publications

References 54 publications

Recent Progress on Polymer Materials for Additive Manufacturing

Recent Progress on Polymer Materials for Additive Manufacturing

Controlled Release of Flurbiprofen from 3D-Printed and Supercritical Carbon Dioxide Processed Methacrylate-Based Polymer

Development and optimization of polypropylene-based powders for selective laser sintering

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