Post-stroke disability and its predictors among Nigerian stroke survivors

Oyewole, Olufemi O.; Ogunlana, Michael O.; Oritogun, Kolawole S; Gbiri, Caleb Ademola

doi:10.1016/j.dhjo.2016.05.011

Cited by 34 publications

(20 citation statements)

References 22 publications

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“…We also found that physical illness or disability significantly predicted CBVD reoccurence, in line with conclusions from a previous meta-analysis10 that history of stroke associated with worse physical state was associated with higher risk of recurrent ischaemic stroke (pooled risk ratio (RR): 2.5, 95% CI, 2.1 to 3.1). In terms of functional scores, relationship problems were not associated with recurrent CBVD in the fully adjusted model, although it is possible that lack of support may prompt higher independence, and reduced unhealthy behaviours, reducing risk of relapse 34…”

Section: Discussionsupporting

confidence: 90%

“…Few studies have explored stroke recurrence in stroke survivors with depression,6–9 and these have reported inconsistent results: three studies6 8 9 found that the presence of depression was associated with an increased hazard for stroke recurrence, while Ayerbe et al 7 found that depression at 3 months after stroke was not associated with higher risk of total stroke recurrence over a 5-year follow-up (HR: 0.98). Furthermore, although a number of previous studies have reported findings on possible risk factors such as older age,8 physical illness,10 medications9 11 12 and comorbidities13–15 predicting first or recurrent CBVD in community samples, few have investigated prediction in people with both depression and CBVD history, despite the likelihood that this is a high risk group. Given this gap in evidence, a cohort study was assembled to investigate potential predictors of CBVD recurrence in a cohort of patients with depression and a history of CBVD.…”

Section: Introductionmentioning

confidence: 99%

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Predictors of cerebrovascular event reoccurrence in patients with depression: a retrospective cohort study

et al. 2020

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ObjectivesTo identify predictors of recurrent cerebrovascular morbidity in a cohort of patients with depression and a cerebrovascular disease (CBVD) history.MethodsWe used the Maudsley Biomedical Research Centre Case Register to identify patients aged 50 years or older with a diagnosis of depressive disorder between 2008 and 2017 and a previous history of hospitalised CBVD. Using depression diagnosis as the index date we followed patients until first hospitalised CBVD recurrence or death due to CBVD. Sociodemographic data, symptom and functioning scores of Health of the Nation Outcome Scales, medications and comorbidities were extracted and modelled in multivariate survival analyses to identify predictors of CBVD reoccurrence.ResultsOf 1292 patients with depression and CBVD (mean age 75.6 years; 56.6% female), 264 (20.4%) experienced fatal/non-fatal CBVD recurrence during a median follow-up duration of 1.66 years. In multivariate Cox regression models, a higher risk of CBVD recurrence was predicted by older age (HR, 1.02; 95% CI, 1.01 to 1.04) (p=0.002), physical health problems (moderate to severe HR, 2.47; 95% CI, 1.45 to 4.19) (p=0.001), anticoagulant (HR, 1.40; 95% CI, 1.01 to 1.93) (p=0.041) and antipsychotic medication (HR, 0.66; 95% CI 0.44 to 0.99) (p=0.047). Neither depression severity, mental health symptoms, functional status, nor antidepressant prescribing were significantly associated with CBVD recurrence.ConclusionsApproximately one in five patients with depression and CBVD experienced a CBVD recurrence over a median follow-up time of 20 months. Risk of CBVD recurrence was largely dependent on age and physical health rather than on severity of depressive symptoms, co-morbid mental health or functional problems, or psychotropic prescribing.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Predictors of cerebrovascular event reoccurrence in patients with depression: a retrospective cohort study

et al. 2020

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“…Two instruments were used in this study: (1) WHODAS (WORLD Health Organization Disability Assistance Schedule) questionnaires, used to measur disability level of stroke survivors, and (2) the PSDRS (Post Stroke Depression Rating Scale) questionnaires, which were used to measure post-stroke depression levels. 10 , 11 Data were then analyzed by Product Moment Pearson correlation to investigate the correlation between depression and functional disability levels in post-stroke patients.…”

Section: Design and Methodsmentioning

confidence: 99%

Depression and Functional Disability in Stroke Patients

Astuti

Kusnanto

Novitasari

2020

Journal of Public Health Research

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Background: Stroke patients often suffer from depression, a mental disorder that worsens their condition and slows down the recovery process. Depression is the leading cause of functional disability due to inability to cope with daily stressors and to function independently in their activities. The purpose of this study is to analyze the relationship between depression and functional disability levels in post-stroke patients. Design and Methods: This is an analytic observational research with a cross-sectional approach. The population in exam consisted of all 4-12 week post-stroke patient in the hospital (about 139 patients). The study focused on 104 respondents, who were selected using simple random sampling techniques. Results: The results show that 62.5% stroke patients suffered mild depressive episodes after the stroke while 58.7% experienced mild disabilities. Analysis results using the Pearson Product Moment Test obtained P=0,000. This shows there is a relationship between the level of depression and the degree of functional disability in post-stroke patients. Conclusions: It can be concluded that there is a significant relationship between the levels of post-stroke depression and the functional disability. Families are expected to provide a safe, supportive, and comfortable environment to lessen the level of depression.

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“…[ 1 ] Medical advances have produced an increasing number of stroke survivors, but many survivors will experience varying degrees of disability. [ 2 ] Most patients are often accompanied by language disability, limb hemiplegia and other dysfunctions when discharge and the rehabilitation of these functions need 6 months or even longer. This makes the patients and their families to fall into the troubles of “adaptation” and “care”, [ 3 ] causes huge impact on the mental health of caregivers and brings a heavy burden.…”

Section: Introductionmentioning

confidence: 99%

Relationship between the anxiety/depression and care burden of the major caregiver of stroke patients

et al. 2018

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To investigate the anxiety/depression of caregivers of stroke patients.This study used a cross-sectional survey design and convenience sampling.Totally, 117 caregivers of stroke patients were enrolled. Data were collected from questionnaires. Hamilton anxiety scale, Hamilton depression scale, and Zarit caregiver burden interview were performed. Multiple linear regression and correlation analysis were used.The anxiety score, depression score and total burden score of 117 stroke caregivers were 16.56 ± 8.02, 18.63 ± 9.39, and 25.88 ± 10.35, respectively. Anxiety symptoms, mild to moderate depressive symptoms, and severe depressive symptoms were found in 43.9%, 26.5%, and 27.4% of the caregivers, respectively. Daily care time and medical payment method were influencing factors for anxiety and depression (P < .05). Both anxiety and depression were positively correlated with total care burden score (P < .01).Anxiety and depression are common in the caregivers of stroke patients and are closely related to care burdens. In this regard, appropriate home care guidance, psychological counseling and social support should be provided to the caregivers to reduce their physical and mental burden.

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Post-stroke disability and its predictors among Nigerian stroke survivors

Cited by 34 publications

References 22 publications

Predictors of cerebrovascular event reoccurrence in patients with depression: a retrospective cohort study

Predictors of cerebrovascular event reoccurrence in patients with depression: a retrospective cohort study

Depression and Functional Disability in Stroke Patients

Relationship between the anxiety/depression and care burden of the major caregiver of stroke patients

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