Post-training vasopressin injections may facilitate or delay shuttle-box avoidance extinction

Hagan, James J.; Bohus, B.; Wied, D. de

doi:10.1016/s0163-1047(82)90843-3

Cited by 23 publications

(1 citation statement)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Aside from its positive effect on memory consolidation, there is also evidence that vasopressin enhances memory retrieval on a passive-avoidance task (Bohus et al, 1978). Failures to obtain a vasopressin enhancement of memory on aversive tasks may be explained, in part, on the basis of ineffective dosage levels (Hagen, Bohus, & De Wied, 1982), inadequate pretraining (Rigter, 1982), or to other treatment or task related variables (Crine, 1982).…”

mentioning

confidence: 99%

Effect of lysine-8-vasopressin on retention and retrieval of a discrimination reward task in the rat.

Mulvey¹,

Watt²,

McEwen³

et al. 1988

Behavioral Neuroscience

View full text Add to dashboard Cite

The effect of vasopressin on memory of a brightness discrimination reward task was investigated in 20 male Sprague-Dawley rats. Two measures of retention were used: resistance to extinction and savings scores on a reacquisition task given 45 days after the completion of extinction training. The effect of the peptide on both memory consolidation and retrieval was assessed. There were two major findings: (a) The peptide enhanced memory consolidation of the task whether measured after a short time interval (6 days) or after a long time interval (45 days after completion of extinction training) using a measure of trials to relearn the task, and (b) the peptide had no effect on memory retrieval. These results were compared to those of other studies designed to access memory consolidation and retrieval on appetitive tasks. The mechanisms of the peptide's effect on memory was briefly discussed with respect to three theories on the subject. This study extends the vasopressin research on memory consolidation by suggesting that it pertains to appetitive as well as to aversive tasks.

show abstract

mentioning

confidence: 99%